Effects of radiotherapy on parotid salivary sialochemistry in head and neck cancer patients

被引：2
|
作者：
Gupta, S. C. [1 ]
Singla, Alok [1 ]
Singh, Mangal [1 ]
Thaliath, B. Paul [1 ]
Geeta, Jaiswal [1 ]
机构：
[1] MLN Med Coll, Dept ENT & Head & Neck Surg, Allahabad 211001, Uttar Pradesh, India
来源：
INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY | 2009年 / 61卷 / 04期
关键词：
Radiotherapy; Head and neck cancer; Parotid gland; Sodium; GLAND FUNCTION; RADIATION; XEROSTOMIA; SECRETION; FLORA;
D O I：
10.1007/s12070-009-0084-7
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
To determine the effects of high dose irradiation on parotid salivary sodium and pH concentration at subsequent duration of 1.5, 3 and 6 months following radiotherapy. Eighty parotid glands of head and neck cancer patients were irradiated with mean dose of 66 Gy. The stimulated parotid flow (PF) was collected by a cannulation of Stenson's duct followed by analysis of sodium (PF sodium) by Easylyte Sodium/Potassium auto analyzer and pH by litmus narrow band pH paper. A steep elevation of PF sodium was found in post-RT period after 1.5 months of starting RT followed by gradual increase up to 6 months and pH changed towards acidity. A high dose of 66 Gy causes irreversible damage to parotid salivary duct system.
引用
收藏
页码：286 / 290
页数：5
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