Metal-Free Visible-Light-Mediated Desulfurization and Aromatization of Dihydropyrimidine-2-thiones for Synthesis of 2-Unsubstituted Pyrimidines

被引：5
|
作者：
Yang, Tian-Yao [1 ,2 ]
Wang, Xi-Cun [1 ,2 ]
Quan, Zheng-Jun [1 ,2 ]
机构：
[1] Minist Educ China, Key Lab Ecoenvironm Related Polymer Mat, Lanzhou 730070, Gansu, Peoples R China
[2] Northwest Normal Univ, Coll Chem & Chem Engn, Key Lab Polymer Mat, Lanzhou 730070, Gansu, Peoples R China
来源：
SYNLETT | 2017年 / 28卷 / 07期
基金：
中国国家自然科学基金;
关键词：
photoredox reactions; organocatalysis; desulfurization; aromatization; dihydropyrimidinethiones; CALCIUM-CHANNEL BLOCKERS; PHOTOREDOX CATALYSIS; BIGINELLI-TYPE; ACID-ESTERS; PHOTOCATALYSIS; FUNCTIONALIZATION; OXIDATION; POTENT; BONDS;
D O I：
10.1055/s-0036-1588401
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The visible-light-mediated aerobic desulfurization and aromatization of Biginelli 3,4-dihydropyrimidine-2(1H)-thiones for a onestep synthesis of 2-unsubstituted pyrimidines was established. The protocol uses molecular oxygen as an inexpensive oxidant, with visible-light irradiation, and eosin B as an organophotoredox catalyst.
引用
收藏
页码：847 / 850
页数：4
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