Cost-effectiveness analysis of a cervical cancer vaccine in five Latin American countries

被引：33
|
作者：
Colantonio, Lisandro [1 ,2 ]
Gomez, Jorge A. [3 ]
Demarteau, Nadia [4 ,5 ]
Standaert, Baudouin [5 ]
Pichon-Riviere, Andres [1 ,2 ]
Augustovski, Federico [1 ,2 ,6 ]
机构：
[1] Inst Clin Effectiveness & Hlth Policy IECS, Buenos Aires, DF, Argentina
[2] Univ Buenos Aires, Sch Publ Hlth, RA-1053 Buenos Aires, DF, Argentina
[3] GlaxoSmithKline Biol, Buenos Aires, DF, Argentina
[4] IMS HEOR, Brussels, Belgium
[5] GlaxoSmithKline Biol, Rixensart, Belgium
[6] Hosp Italiano Buenos Aires, Family & Community Med Div, Buenos Aires, DF, Argentina
来源：
VACCINE | 2009年 / 27卷 / 40期
关键词：
Papillomavirus vaccines; Uterine cervical neoplasms; Cost-effectiveness analysis; HUMAN-PAPILLOMAVIRUS TYPE-16; HPV VACCINATION; CONVENTIONAL CYTOLOGY; PARTICLE VACCINE; MEXICAN WOMEN; HEALTH; PREVALENCE; PREVENTION; INFECTION; LESIONS;
D O I：
10.1016/j.vaccine.2009.06.097
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Implementation of cervical cancer (CC) vaccination in Latin America is expected to reduce the high CC burden in those countries. But the efficiency of such vaccination programs in the region still remains unknown. This study assesses the cost-effectiveness and cost-utility of introducing vaccination into the current CC disease management of five Latin American countries (Argentina, Brazil, Chile, Mexico, and Peru). The modelling results indicate that universal mass vaccination is cost-effective in the current health care setting of each country (<3x gross domestic product per capita, per country) with a substantial number of CC cases and deaths avoided in addition to an increase of quality-adjusted life years. This study will help guide the design of future clinical programmes and health-related policies. It will assist early and effective decision-making processes related to vaccine implementation in Latin America. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5519 / 5529
页数：11
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