HER2/neu;
monoclonal antibody;
breast cancer;
trastuzumab;
adjuvant therapy;
D O I:
10.1159/000094891
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Immunotherapy with the monoclonal antibody trastuzumab is a well established cornerstone of an individualized treatment strategy for women with HER2/neu-over-expressing breast cancer. Based on the reported data of clinical studies comprising more than 14,000 women, trastuzumab was approved throughout the European Union in May 2006 for adjuvant therapy in patients with early-stage HER2/neu-overexpressing breast cancer.
机构:
Fox Chase Canc Ctr, Div Med Sci, Dept Med Oncol, Philadelphia, PA 19111 USAFox Chase Canc Ctr, Div Med Sci, Dept Med Oncol, Philadelphia, PA 19111 USA
Mehra, Ranee
Burtness, Barbara
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h-index: 0
机构:
Fox Chase Canc Ctr, Div Med Sci, Dept Med Oncol, Philadelphia, PA 19111 USAFox Chase Canc Ctr, Div Med Sci, Dept Med Oncol, Philadelphia, PA 19111 USA
机构:
Inst Portugues Oncol Francisco Gentil, Med Oncol Serv, Lisbon, PortugalInst Portugues Oncol Francisco Gentil, Med Oncol Serv, Lisbon, Portugal
Oliveira, M.
Nave, M.
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机构:
Hosp Luz, Med Oncol Unit, Lisbon, PortugalInst Portugues Oncol Francisco Gentil, Med Oncol Serv, Lisbon, Portugal
Nave, M.
Gil, N.
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h-index: 0
机构:
Hosp Luz, Med Oncol Unit, Lisbon, PortugalInst Portugues Oncol Francisco Gentil, Med Oncol Serv, Lisbon, Portugal
Gil, N.
Passos-Coelho, J. L.
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h-index: 0
机构:
Inst Portugues Oncol Francisco Gentil, Med Oncol Serv, Lisbon, Portugal
Hosp Luz, Med Oncol Unit, Lisbon, PortugalInst Portugues Oncol Francisco Gentil, Med Oncol Serv, Lisbon, Portugal