Adjuvant antibody therapy with trastuzumab in early breast cancer

被引:0
|
作者
Untch, Michael
Scharl, Anton
Jackisch, Christian
Thomssen, Christoph
Nitz, Ulrike
von Minckwitz, Gunter
Harbeck, Nadia
机构
[1] Univ Charite, Akad LK, Helios Klinikum Berlin Buch, Frauenklin,Interdisziplinaires Brustzentrum, D-13125 Berlin, Germany
[2] Frauenklin Amberg, Amberg, Germany
[3] Frauenklin Offenbach, Offenbach, Germany
[4] Univ Halle Wittenberg, Frauenklin, D-4010 Halle, Germany
[5] Univ Dusseldorf, Frauenklin, D-4000 Dusseldorf, Germany
[6] GBG Forsch GmbH, Neu Isenburg, Germany
[7] Tech Univ Munich, Frauenklin, D-8000 Munich, Germany
关键词
HER2/neu; monoclonal antibody; breast cancer; trastuzumab; adjuvant therapy;
D O I
10.1159/000094891
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Immunotherapy with the monoclonal antibody trastuzumab is a well established cornerstone of an individualized treatment strategy for women with HER2/neu-over-expressing breast cancer. Based on the reported data of clinical studies comprising more than 14,000 women, trastuzumab was approved throughout the European Union in May 2006 for adjuvant therapy in patients with early-stage HER2/neu-overexpressing breast cancer.
引用
收藏
页码:252 / 255
页数:4
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