Motivational deficits as the central link to functioning in schizophrenia: A pilot study

被引：80
|
作者：
Foussias, G. [1 ,2 ,3 ]
Mann, S. [1 ,2 ,3 ]
Zakzanis, K. K. [4 ]
van Reekum, R. [3 ]
Remington, G. [1 ,2 ,3 ]
机构：
[1] Univ Toronto, Ctr Addict & Mental Hlth, Toronto, ON M5T 1R8, Canada
[2] Univ Toronto, Dept Psychiat, Toronto, ON M5T 1R8, Canada
[3] Univ Toronto, Inst Med Sci, Fac Med, Toronto, ON M5S 1A8, Canada
[4] Univ Toronto Scarborough, Dept Psychol, Toronto, ON M1C 1A4, Canada
来源：
SCHIZOPHRENIA RESEARCH | 2009年 / 115卷 / 2-3期
基金：
加拿大健康研究院;
关键词：
Motivation; Apathy; Pleasure; Cognition; Schizophrenia; Functioning; NEGATIVE SYMPTOMS; RATING-SCALE; FLAT AFFECT; EXPERIENCE; RELIABILITY; ANHEDONIA; APATHY; 1ST-EPISODE; VALIDATION; COMPONENTS;
D O I：
10.1016/j.schres.2009.09.020
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Negative symptoms have consistently been found to contribute to functional impairment in schizophrenia. In this pilot study, we sought to delineate the core negative symptoms that contribute to this functional impairment. Adult outpatients with schizophrenia were evaluated for the severity of positive, negative, cognitive, and depressive symptoms. The Quality of Life Scale was used to assess current functioning. Results from 21 participants revealed that amotivation was the sole predictor of functioning, accounting for 74% of the variance in current functioning. This suggests that motivational deficits are the central link between negative symptoms and functional impairment in schizophrenia. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码：333 / 337
页数：5
相关论文
共 50 条
  • [1] THE MODERATING ROLE OF MOTIVATIONAL DEFICITS ON NEUROCOGNITIVE FUNCTIONING ACROSS THE COURSE OF SCHIZOPHRENIA
    Biagianti, Bruno
    Schlosser, Danielle
    Loewy, Rachel
    Vinogradov, Sophia
    [J]. SCHIZOPHRENIA BULLETIN, 2015, 41 : S162 - S162
  • [2] MOTIVATIONAL DEFICITS IN SCHIZOPHRENIA: CROSS-SECTIONAL AND LONGITUDINAL RELATIONSHIPS WITH FUNCTIONING
    Foussias, George
    Mann, Steve
    Zakzanis, Konstantine K.
    van Reekum, Rob
    Agid, Ofer
    Remington, Gary
    [J]. SCHIZOPHRENIA RESEARCH, 2010, 117 (2-3) : 303 - 304
  • [3] Motivational and neurocognitive deficits are central to the prediction of longitudinal functional outcome in schizophrenia
    Fervaha, G.
    Foussias, G.
    Agid, O.
    Remington, G.
    [J]. ACTA PSYCHIATRICA SCANDINAVICA, 2014, 130 (04) : 290 - 299
  • [4] Smoking and cognitive deficits in schizophrenia: A pilot study
    Taiminen, TJ
    Salokangas, RKR
    Saarijarvi, S
    Niemi, H
    Lehto, H
    Ahola, V
    Syvalahti, E
    [J]. ADDICTIVE BEHAVIORS, 1998, 23 (02) : 263 - 266
  • [5] Motivational Deficits and Cognitive Test Performance in Schizophrenia
    Fervaha, Gagan
    Zakzanis, Konstantine K.
    Foussias, George
    Graff-Guerrero, Ariel
    Agid, Ofer
    Remington, Gary
    [J]. JAMA PSYCHIATRY, 2014, 71 (09) : 1058 - 1065
  • [6] BASELINE MOTIVATIONAL DEFICITS AS THE KEY PREDICTOR OF FUNCTIONING IN SCHIZOPHRENIA AT 1-YEAR FOLLOW-UP
    Foussias, George
    Mann, Steve
    Zakzanis, Konstantine K.
    van Reekum, Rob
    Agid, Ofer
    Remington, Gary
    [J]. SCHIZOPHRENIA BULLETIN, 2011, 37 : 265 - 265
  • [7] Intellectual functioning and memory deficits in schizophrenia
    Ruiz, Juan Carlos
    Soler, Maria Jose
    Fuentes, Inma
    Tomas, Pilar
    [J]. COMPREHENSIVE PSYCHIATRY, 2007, 48 (03) : 276 - 282
  • [8] Social functioning deficits in the schizophrenia prodrome
    Marks, I
    Royston, N
    Cadenhead, KS
    [J]. BIOLOGICAL PSYCHIATRY, 2005, 57 (08) : 59S - 59S
  • [9] A COMPUTATIONAL ANALYSIS OF MOTIVATIONAL DEFICITS IN SCHIZOPHRENIA SPECTRUM DISORDERS
    Waltz, James
    Hernaus, Dennis
    Wilson, Robert
    Brown, Elliot
    Frank, Michael
    Gold, James
    [J]. SCHIZOPHRENIA BULLETIN, 2020, 46 : S255 - S255
  • [10] Cognitive deficits and community functioning in chronic schizophrenia
    Galderisi, S
    Piegari, G
    Mucci, A
    Mancuso, F
    Acerra, A
    Volpe, M
    Valente, A
    Maj, M
    [J]. SCHIZOPHRENIA RESEARCH, 2006, 81 : 127 - 127
12345