Inhibition of the MET oncogene kinase domain or ligand binding site abrogates an invasive phenotype in human colorectal cancer

被引：0
|
作者：
Francone, T. D.
Chen, T. C.
Sun, M.
Zeng, Z.
Nakamura, T.
Matsumoto, K.
Paty, P. B.
Weiser, M. R.
机构：
[1] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA
[2] Osaka Univ, Grad Sch Med, Osaka, Japan
来源：
ANNALS OF SURGICAL ONCOLOGY | 2007年 / 14卷 / 02期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：20 / 21
页数：2
相关论文
共 50 条
  • [1] Retrogenic expression of the MET proto-oncogene correlates with the invasive phenotype of human rhabdomyosarcomas
    Ferracini, R
    Olivero, M
    DiRenzo, MF
    Martano, M
    DeGiovanni, C
    Nanni, P
    Basso, G
    Scotlandi, K
    Lollini, PL
    Comoglio, PM
    ONCOGENE, 1996, 12 (08) : 1697 - 1705
  • [2] Novel mutation in the ATP-binding site of the MET oncogene tyrosine kinase in a HPRCC family
    Olivero, M
    Valente, G
    Bardelli, A
    Longati, P
    Ferrero, N
    Cracco, C
    Terrone, C
    Rocca-Rossetti, S
    Comoglio, PM
    Di Renzo, MF
    INTERNATIONAL JOURNAL OF CANCER, 1999, 82 (05) : 640 - 643
  • [3] HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells
    Bachleitner-Hofmann, Thomas
    Sun, Mark Y.
    Chen, Chin-Tung
    Tang, Laura
    Song, Lin
    Zeng, Zhaoshi
    Shah, Manish
    Christensen, James G.
    Rosen, Neal
    Solit, David B.
    Weiser, Martin R.
    MOLECULAR CANCER THERAPEUTICS, 2008, 7 (11) : 3499 - 3508
  • [4] Clinical significance of c-met oncogene alterations in human colorectal cancer
    Umeki, K
    Shiota, G
    Kawasaki, H
    ONCOLOGY, 1999, 56 (04) : 314 - 321
  • [5] Mechanisms of MET Dysregulation and ligand-dependency in human colorectal cancer
    Francone, T
    Chen, TC
    Kuntz, E
    Zeng, Z
    Paty, PB
    Weiser, MR
    ANNALS OF SURGICAL ONCOLOGY, 2006, 13 (02) : 2 - 2
  • [6] The role of c-MET/HGF signaling as a critical mediator of an invasive and resistant phenotype in colorectal cancer
    Bradley, Conor A.
    Dunne, Philip
    McArt, Darragh
    Arthur, Ken
    McQuaid, Stephen
    Salto-Tellez, Manuel
    Johnston, Patrick
    Van Schaeybroeck, Sandra
    CANCER RESEARCH, 2015, 75
  • [7] Autophosphorylation Activates Dictyostelium Myosin II Heavy Chain Kinase A by Providing a Ligand for an Allosteric Binding Site in the α-Kinase Domain
    Crawley, Scott W.
    Gharaei, Mojdeh Samimi
    Ye, Qilu
    Yang, Yidai
    Raveh, Barak
    London, Nir
    Schueler-Furman, Ora
    Jia, Zongchao
    Cote, Graham P.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (04) : 2607 - 2616
  • [8] Inhibition of HER3 and MET as combination targeted therapy in human colorectal cancer
    Yamasaki, Akitaka
    Hara, Yuta
    Masuko, Takashi
    CANCER SCIENCE, 2018, 109 : 1377 - 1377
  • [9] Mutations in the ligand-binding domain of the kit receptor: An uncommon site in human piebaldism
    Fleischman, RA
    Gallardo, T
    Mi, XF
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1996, 107 (05) : 703 - 706
  • [10] Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein
    Peschard, P
    Fournier, TM
    Lamorte, L
    Naujokas, MA
    Band, H
    Langdon, WY
    Park, M
    MOLECULAR CELL, 2001, 8 (05) : 995 - 1004
12345