Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

被引：11
|
作者：
van Soest, G. [1 ]
Goderie, T. P. M. [1 ]
Gonzalo, N. [2 ]
Koljenovic, S. [3 ]
van Leenders, G. L. J. H. [3 ]
Regar, E. [2 ]
Serruys, P. W. [2 ]
van der Steen, A. F. W. [1 ,4 ]
机构：
[1] Erasmus MC, Ctr Thorax, Dept Biomed Engn, NL-3000 CA Rotterdam, Netherlands
[2] Erasmus MC, Ctr Thorax, Dept Intervent Cardiol, NL-3000 CA Rotterdam, Netherlands
[3] Erasmus MC, Dept Pathol, NL-3000 CA Rotterdam, Netherlands
[4] Interuniv Cardiol Inst Netherlands, Rotterdam, Netherlands
来源：
NETHERLANDS HEART JOURNAL | 2009年 / 17卷 / 11期
关键词：
atherosclerosis; optical coherence tomography; intravascular imaging; tissue characterisation; VULNERABLE PLAQUE; CORONARY; ULTRASOUND; RUPTURE; CULPRIT; LESION; CAP;
D O I：
10.1007/BF03086301
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient It, distinguishes different tissue types: necrotic core and macrophage infiltration exhibit strong attenuation, mu(t)>= 10 mm(-1), while calcific and fibrous tissue have a lower mu(t)approximate to 2-5 mm(-1). (Neth Heart J 2009;17:448-50.)
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页码：448 / 450
页数：3
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