Introduction of Bovine-Based Nutrient Fortifier and Gastrointestinal Inflammation in Very Low Birth Weight Infants as Measured by Fecal Calprotectin

被引：13

作者：

Panczuk, Julia K. ^{[1
]}

Unger, Sharon ^{[1
,2
]}

Francis, Jane ^{[3
]}

Bando, Nicole ^{[3
]}

Kiss, Alex ^{[4
]}

O'Connor, Deborah L. ^{[3
,5
]}

机构：

[1] Univ Toronto, Dept Pediat, Toronto, ON, Canada

[2] Mt Sinai Hosp, Toronto, ON M5G 1X5, Canada

[3] Hosp Sick Children, Dept Nutr Sci, 555 Univ Ave, Toronto, ON M5G 1X8, Canada

[4] Sunnybrook Res Inst, Toronto, ON, Canada

[5] Hosp Sick Children, Res Inst, 555 Univ Ave, Toronto, ON M5G 1X8, Canada

来源：

BREASTFEEDING MEDICINE | 2016年 / 11卷 / 01期

基金：

加拿大健康研究院;

关键词：

NECROTIZING ENTEROCOLITIS; HUMAN-MILK; L1;

D O I：

10.1089/bfm.2015.0125

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Background: Fecal calprotectin (fCP) is a biomarker of gastrointestinal tract (GIT) inflammation that is currently being used investigationally among very low birth weight (VLBW) infants. Materials and Methods: Stool was collected weekly from 20 breastmilk-fed VLBW infants for up to 8 weeks after birth during the establishment and fortification of feeds, and fCP concentrations were measured. Results: Mean fCP levels increased significantly in stools collected immediately following bovine-based nutrient fortification of feeds (p=0.005). Conclusions: Addition of bovine fortifier to breastmilk feeds appeared to be associated with an acute increase in GIT inflammation.

引用

页码：2 / 5

页数：4

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