Asthenozoospermia: Cellular and molecular contributing factors and treatment strategies

被引：89
|
作者：
Shahrokhi, Seyedeh Zahra [1 ]
Salehi, Peyman [2 ]
Alyasin, Atieh [3 ]
Taghiyar, Sana [4 ]
Deemeh, Mohammad Reza [4 ,5 ]
机构：
[1] Shahid Beheshti Univ Med Sci, Sch Allied Med Sci, Dept Lab Med, Tehran, Iran
[2] Shahid Beheshti Hosp, Infertil Ctr, Esfahan, Iran
[3] Arak Univ, Dept Biol, Arak, Iran
[4] Nobel Lab, Androl Dept, Esfahan, Iran
[5] Tarbiat Modares Univ, Dept Clin Biochem, Fac Med Sci, Tehran, Iran
来源：
ANDROLOGIA | 2020年 / 52卷 / 02期
关键词：
apoptosis; reactive oxygen species; spermiogenesis; MITOCHONDRIAL RESPIRATORY EFFICIENCY; CAUSES MALE-INFERTILITY; SEMEN PARAMETERS; ION CHANNELS; REGULATORY MECHANISMS; SPERM MOTILITY; FIBROUS SHEATH; DIETARY SUPPLEMENTATION; CLOMIPHENE CITRATE; DOUBLE-BLIND;
D O I：
10.1111/and.13463
中图分类号：
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
摘要：
Semen sample with poor sperm motility, which called asthenozoospermia, is considered as one of the main factors contributing to male infertility. Recognition of the cellular and molecular pathways contributing to sperm motility reduction may lead to applying novel treatment strategies for overcoming low sperm motility in asthenozoospermia individuals. In this review, we intend to discuss the main causes of sperm motility reduction in asthenozoospermia and some treatment strategies used to overcome low sperm motility.
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页数：11
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