Modifiers of risk of hereditary breast and ovarian cancer

被引:122
|
作者
Narod, SA [1 ]
机构
[1] Univ Toronto, Womens Coll Hosp, Ctr Res Womens Hlth, Toronto, ON M5G 1N8, Canada
关键词
D O I
10.1038/nrc726
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Hereditary breast and ovarian cancer is among the most commonly encountered adult genetic disease, and it is increasingly important that geneticists, oncologists, surgeons and gynaecologists are aware of the issues regarding risk assessment, prevention and management of women with inherited susceptibility to cancer. Genetic risk can be modified by external factors, but what are these factors, and how might our knowledge of them help us to better define the risks for individual women and to develop strategies for cancer prevention?
引用
收藏
页码:113 / +
页数:12
相关论文
共 50 条
  • [1] Modifiers of risk of hereditary breast and ovarian cancer
    Steven A. Narod
    [J]. Nature Reviews Cancer, 2002, 2 : 113 - 123
  • [2] Modifiers of risk of hereditary breast cancer
    S A Narod
    [J]. Oncogene, 2006, 25 : 5832 - 5836
  • [3] Modifiers of risk of hereditary breast cancer
    Narod, S. A.
    [J]. ONCOGENE, 2006, 25 (43) : 5832 - 5836
  • [4] Identifying and managing hereditary risk of breast and ovarian cancer
    Frank, TS
    Critchfield, GC
    [J]. CLINICS IN PERINATOLOGY, 2001, 28 (02) : 395 - +
  • [5] Breast and Ovarian Cancer Hereditary Risk Assessment Program
    Wallace, Charlenc
    [J]. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2008, 31 (05): : 512 - 512
  • [6] Laboratory identification of hereditary risk of breast and ovarian cancer
    Frank, TS
    [J]. CURRENT OPINION IN BIOTECHNOLOGY, 1999, 10 (03) : 289 - 294
  • [7] The prevalence of hereditary breast/ovarian cancer risk in patients with a history of breast or ovarian cancer in Japanese subjects
    Komata, Dai
    Yahata, Tetsuro
    Kodama, Shoji
    Koyama, Yu
    Takeda, Nobuo
    Tajima, Kenzo
    Makino, Haruhiko
    Sato, Nobuaki
    Muto, Ichiro
    Hatakeyama, Katsuyoshi
    Tanaka, Kenichi
    [J]. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, 2009, 35 (05) : 912 - 917
  • [8] Risk Perception Among Women at Risk for Hereditary Breast and Ovarian Cancer
    Pilarski, Robert
    [J]. JOURNAL OF GENETIC COUNSELING, 2009, 18 (04) : 303 - 312
  • [9] Gastrointestinal cancer risk in Irish hereditary breast ovarian cancer families
    Gogarty, Darragh S.
    Lyons, Tomas
    Farrell, Michael P.
    Dorman, Naoise Maria
    Green, Andrew J.
    Gallagher, David J.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (04)
  • [10] Managing hereditary breast cancer risk in women with and without ovarian cancer
    Peters, Mary Linton
    Garber, Judy E.
    Tung, Nadine
    [J]. GYNECOLOGIC ONCOLOGY, 2017, 146 (01) : 205 - 214