The International Transporter Consortium: A Collaborative Group of Scientists From Academia, Industry, and the FDA

被引：56

作者：

Huang, S-M ^{[2
]}

Zhang, L. ^{[2
]}

Giacomini, K. M. ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94143 USA

[2] US FDA, Off Clin Pharmacol, Off Translat Sci, Ctr Drug Evaluat & Res, Silver Spring, MD USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2010年 / 87卷 / 01期

关键词：

DRUG-DRUG INTERACTIONS; EFFLUX TRANSPORTERS; KIDNEY; IMPACT; LIVER; OATP;

D O I：

10.1038/clpt.2009.236

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The US Food and Drug Administration-led Critical Path Initiative, launched in 2004, has resulted in an array of activities focused on the sciences that support the development of human medical products.(1) These activities include the development of new scientific tools, such as in vitro testing, qualified biomarkers of drug safety, and innovative new methods in study design and data analysis.(2) As a result of the Critical Path Initiative and enormous advances in the field of membrane transporters, the International Transporter Consortium was formed.

引用

页码：32 / 36

页数：5

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