Targeting Oxygen in Term and Preterm Infants Starting at Birth

被引：9
|
作者：
Vento, Maximo [1 ]
Saugstad, Ola Didrik [2 ,3 ,4 ]
机构：
[1] Univ & Polytech Hosp La Fe, Div Neonatol, Ave Fernando Abril Martorell 106, Valencia 46026, Spain
[2] Univ Oslo, Oslo Univ Hosp, Dept Pediat Res, Postboks 4950 Nydalen, N-0424 Oslo, Norway
[3] Robert H Lurie Med Res Ctr, Dept Pediat, Chicago, IL USA
[4] Northwestern Univ, Evanston, IL USA
来源：
CLINICS IN PERINATOLOGY | 2019年 / 46卷 / 03期
关键词：
Oxygen; Resuscitation; Newborn infant; Preterm; Oxygen saturation; Pulse oximetry; PREVENTS OXIDATIVE STRESS; ROOM-AIR; NEWBORN-INFANTS; NEONATAL RESUSCITATION; 100-PERCENT OXYGEN; GLUTATHIONE METABOLISM; ANTIOXIDANT ENZYMES; HYPEROXIC EXPOSURE; PREMATURE RABBITS; GLOBAL BURDEN;
D O I：
10.1016/j.clp.2019.05.013
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Transition into the extrauterine world is characterized by a substantial increase in oxygen availability to tissue. Exact oxygen provision may be needed to avoid negative consequences of hypoxia or hyperoxia. For term and near-term infants, it is recommended to start with air and titrate the oxygen supplement to the saturation nomogram. However, oxygen supplementation in infants less than 32 weeks' gestation is an unsolved conundrum. At present, the inspired fraction of oxygen is set according to gestational age and blended to achieve targeted saturations and heart rates. Studies are still needed to overcome uncertainties about oxygen supplementation during preterm stabilization.
引用
收藏
页码：459 / +
页数：16
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