The role of oxidative stress in the pathogenesis and therapy of chronic wounds

被引：0
|
作者：
Dissemond, J [1 ]
Goos, M [1 ]
Wagner, SN [1 ]
机构：
[1] Univ Essen Gesamthsch Klinikum, Klin & Poliklin Dermatol Venerol & Allergol, D-45147 Essen, Germany
来源：
HAUTARZT | 2002年 / 53卷 / 11期
关键词：
oxygen; wound healing; reactive oxygen species; oxidative stress; antioxidants;
D O I：
10.1007/s00105-001-0325-5
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Molecular oxygen plays a central role in the pathogenesis and therapy of chronic wounds. When reactive oxygen species are overproduced, oxidative stress results, with detrimental cytotoxic effects causing delayed wound healing. Therefore,elimination of reactive oxygen species could be an important strategy to improve healing of chronic wounds. Currently first therapeutic strategies targeting reactive oxygen species by antioxidants are being introduced into the treatment of chronic wounds.
引用
收藏
页码：718 / 723
页数：6
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