EVALUATION OF [11C]PBR28 PET IMAGING TO DETECT CHANGES IN MICROGLIAL ACTIVATION IN MOUSE MODELS OF ALZHEIMER'S DISEASE

被引:0
|
作者
Tang, S. P. [1 ]
Mirzaei, N. [2 ]
Coello, C. [1 ]
Ashworth, S. [1 ]
Weekes, A. [1 ]
Plisson, C. [1 ]
Passchier, J. [1 ]
Tyacke, R. J. [2 ]
Nutt, D. [2 ]
Sastre, M. [2 ]
机构
[1] Imanova Ltd, Imanova, London, England
[2] Imperial Coll, Div Brain Sci, London, England
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
820
引用
收藏
页码:654 / 655
页数:2
相关论文
共 50 条
  • [1] Microglial depletion and activation: A [11C]PBR28 PET study in nonhuman primates
    Ansel T. Hillmer
    Daniel Holden
    Krista Fowles
    Nabeel Nabulsi
    Brian L. West
    Richard E. Carson
    Kelly P. Cosgrove
    [J]. EJNMMI Research, 7
  • [2] Microglial depletion and activation: A [11C] PBR28 PET study in nonhuman primates
    Hillmer, Ansel T.
    Holden, Daniel
    Fowles, Krista
    Nabulsi, Nabeel
    West, Brian L.
    Carson, Richard E.
    Cosgrove, Kelly P.
    [J]. EJNMMI RESEARCH, 2017, 7
  • [3] [11C]PBR28 imaging in a mouse model of Alexander disease
    Lao, Patrick
    Betthauser, Tobey
    Hagemann, Tracy
    Barnhart, Todd
    Messing, Albee
    Christian, Bradley
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (03)
  • [4] In Vivo Imaging of Microglial Activation by Positron Emission Tomography with [11C] PBR28 in the 5XFAD Model of Alzheimer's Disease
    Mirzaei, Nazanin
    Sac Pham Tang
    Ashworth, Sharon
    Coello, Christopher
    Plisson, Christophe
    Passchier, Jan
    Selvaraj, Vimal
    Tyacke, Robin J.
    Nutt, David J.
    Sastre, Magdalena
    [J]. GLIA, 2016, 64 (06) : 993 - 1006
  • [5] Utility of [11C] PBR28 PET in the imaging of inflammatory arthritis
    Narayan, Nehal
    Coello, Christopher
    Saleem, Azeem
    Taylor, Peter
    [J]. LANCET, 2017, 389 : 73 - 73
  • [6] [11C]PBR28 inflammatory PET imaging in frontotemporal dementia
    Clarke, M. T.
    Woollacott, I.
    Shafei, R.
    Moore, K.
    Greaves, C.
    Russell, L.
    Neason, M.
    Bocchetta, M.
    Cash, D.
    Rohrer, J.
    [J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2019, 39 : 612 - 613
  • [7] [11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat
    Walker, Matthew D.
    Dinelle, Katherine
    Kornelsen, Rick
    Lee, Nathan V.
    Miao, Qing
    Adam, Mike
    Takhar, Christine
    Mak, Edwin
    Schulzer, Michael
    Farrer, Matthew J.
    Sossi, Vesna
    [J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2015, 35 (08): : 1331 - 1338
  • [8] Systemic endotoxin induces a robust increase in microglial activation measured with [11C]PBR28 and PET in humans
    Sandiego, Christine
    Gallezot, Jean-Dominique
    Lim, Keunpoong
    Lin, Shu-fei
    Devine, Lesley
    O'Connor, Kevin
    Huang, Yiyun
    Hannestad, Jonas
    Carson, Richard
    Cosgrove, Kelly
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (03)
  • [9] FULLY AUTOMATED SYNTHESIS AND INITIAL PET EVALUATION OF [11C]PBR28
    Wang, M.
    Yoder, K.
    Mock, B.
    Gao, M.
    Winkle, W.
    Saykin, A.
    Hutchins, G.
    Zheng, Q.
    [J]. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2009, 52 : S260 - S260
  • [10] Fully automated synthesis and initial PET evaluation of [11C]PBR28
    Wang, Min
    Yoder, Karmen K.
    Gao, Mingzhang
    Mock, Bruce H.
    Xu, Xiao-Ming
    Saykin, Andrew J.
    Hutchins, Gary D.
    Zheng, Qi-Huang
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (19) : 5636 - 5639