Local radiofrequency-induced hyperthermia using CuNi nanoparticles with therapeutically suitable Curie temperature

被引：54
|
作者：
Kuznetsov, Anatoly A.
Leontiev, Vladimir G.
Brukvin, Vladimir A.
Vorozhtsov, Georgy N.
Kogan, Boris Ya.
Shlyakhtin, Oleg A.
Yunin, Alexander M.
Tsybin, Oleg I.
Kuznetsov, Oleg A.
机构：
[1] Russian Acad Sci, Inst Biochem Phys, Moscow 119991, Russia
[2] Russian Acad Sci, Inst Met, Moscow 119991, Russia
[3] NIOPIK Organ Intermediates & Dyes Inst, Moscow 103787, Russia
[4] Russian Acad Sci, Inst Chem Phys, Moscow 119991, Russia
来源：
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2007年 / 311卷 / 01期
关键词：
magnetic fluid hyperthermia; radiofrequency heating; Curie temperature; temperature control by parametric feedback; nanoparticle; copper-nickel alloy; cancer treatment; THERAPY;
D O I：
10.1016/j.jmmm.2006.11.199
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Copper-nickel (CuNi) alloy nanoparticles with Curie temperatures (T-c) from 40 to 60 degrees C were synthesized by several techniques. Varying the synthesis parameters and post-treatment, as well as separations by size and T-c, allow producing mediator nanoparticles for magnetic fluid hyperthermia with parametric feedback temperature control with desired parameters. In vitro and in vivo animal experiments have demonstrated the feasibility of the temperature-controlled heating of the tissue, laden with the particles, by an external alternating magnetic field. (C) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：197 / 203
页数：7
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