Impairment of cell division of Trypanosoma cruzi epimastigotes

被引：1

作者：

Zacks, Michele A. ^{[1
]}

机构：

[1] Univ Texas, Med Branch, Dept Pathol, Galveston, TX 77555 USA

来源：

MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2007年 / 102卷 / 01期

关键词：

Trypanosoma cruzi; life cycle; differentiation;

D O I：

10.1590/S0074-02762007000100019

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The mechanisms that facilitate the adaptation of Trypanosoma cruzi to two distinct hosts, insect and vertebrate, are poorly understood, in part due to the limited ability to perform gene disruption studies by homologous recombination. This report describes a developmentally-defective phenotype that resulted from integration of a drug marker adjacent to the GAPDH gene in T cruzi.

引用

页码：111 / 115

页数：5

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