Owing to the importance of differential equations in physics, the existence of solutions for differential equations has been paid much attention. In this paper, the existence of solution are obtained for the nonlinear second order two-point boundary value problem in the reproducing kernel space. Under certain assumptions on right-hand side, we propose constructive proof for the existence result, and a method is presented to obtain the exact solution expressed by the form of series. This paper is a extension of previous paper [Wei Jiang, Minggen Cui, The exact solution and stability analysis for integral equation of third or first kind with singular kernel, Appl. Math. Comput. 202 (2) (2008) 666-674], which extends a method of solving linear problems to present method for solving nonlinear problems. (C) 2009 Elsevier Inc. All rights reserved.