Re-evaluation of a novel resistance mutation in eccC5 of the ESX-5 secretion system in ofloxacin-resistant Mycobacterium tuberculosis

被引：1
|
作者：
Blackman, Amondrea [1 ,2 ]
Morrison, Bob [3 ]
Maruri, Fernanda [1 ,2 ]
van der Heijden, Yuri [1 ,2 ,4 ]
Nochowicz, Cindy Hager [1 ,2 ]
Guo, Yan [5 ]
Scholz, Matthew [6 ]
Rustad, Tige [3 ]
Sherman, David R. [3 ,7 ]
Sterling, Timothy R. [1 ,2 ]
机构：
[1] Vanderbilt Univ, Sch Med, Dept Med, Div Infect Dis, Nashville, TN 37212 USA
[2] Vanderbilt Univ, Sch Med, Vanderbilt TB Ctr, Nashville, TN 37212 USA
[3] Seattle Childrens Hosp, Seattle, WA USA
[4] Aurum Inst, Johannesburg, South Africa
[5] Univ New Mexico, Albuquerque, NM 87131 USA
[6] Vanderbilt Univ, Med Ctr, Vanderbilt Technol Adv Genom VANTAGE Core, Nashville, TN USA
[7] Univ Washington, Dept Microbiol, Seattle, WA 98195 USA
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2021年 / 76卷 / 03期
关键词：
ASSAY;
D O I：
10.1093/jac/dkaa507
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
引用
收藏
页码：820 / 822
页数：3
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  • [1] A novel resistance mutation in eccC5 of the ESX-5 secretion system confers ofloxacin resistance in Mycobacterium tuberculosis
    Eilertson, Brandon
    Maruri, Fernanda
    Blackman, Amondrea
    Guo, Yan
    Herrera, Miguel
    van der Heijden, Yuri
    Shyr, Yu
    Sterling, Timothy R.
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2016, 71 (09) : 2419 - 2427
  • [2] Modular Organization of the ESX-5 Secretion System in Mycobacterium tuberculosis
    Shah, Swati
    Briken, Volker
    [J]. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2016, 6
  • [3] Species-specific secretion of ESX-5 type VII substrates is determined by the linker 2 of EccC5
    Bunduc, Catalin M.
    Ummels, Roy
    Bitter, Wilbert
    Houben, Edith N. G.
    [J]. MOLECULAR MICROBIOLOGY, 2020, 114 (01) : 66 - 76
  • [4] The ESX-5 Associated eccB5-eccC5 Locus Is Essential for Mycobacterium tuberculosis Viability
    Di Luca, Mariagrazia
    Bottai, Daria
    Batoni, Giovanna
    Orgeur, Mickael
    Aulicino, Anna
    Counoupas, Claudio
    Campa, Mario
    Brosch, Roland
    Esin, Semih
    [J]. PLOS ONE, 2012, 7 (12):
  • [5] New insights into the domain of unknown function (DUF) of EccC5, the pivotal ATPase providing the secretion driving force to the ESX-5 secretion system
    Ceballos-Zuniga, Fernando
    Menendez, Margarita
    Perez-Dorado, Inmaculada
    [J]. ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2024, 80 : 397 - 409
  • [6] Phosphate starvation: a novel signal that triggers ESX-5 secretion in Mycobacterium tuberculosis
    Elliott, Sarah R.
    Tischler, Anna D.
    [J]. MOLECULAR MICROBIOLOGY, 2016, 100 (03) : 510 - 526
  • [7] The ESX-5 Secretion System of Mycobacterium marinum Modulates the Macrophage Response
    Abdallah, M. Abdallah
    Savage, Nigel D. L.
    van Zon, Maaike
    Wilson, Louis
    Vandenbroucke-Grauls, Christina M. J. E.
    van der Wel, Nicole N.
    Ottenhoff, Tom H. M.
    Bitter, Wilbert
    [J]. JOURNAL OF IMMUNOLOGY, 2008, 181 (10): : 7166 - 7175
  • [8] Cloning and Protein Expression of eccB5 Gene in ESX-5 System from Mycobacterium tuberculosis
    Kurniawati, Siti
    Mertaniasih, Ni Made
    Ato, Manabu
    Tamura, Toshiki
    Soedarsono, Soedarsono
    Aulanni'am, Aulanni'am
    Mori, Shigetarou
    Maeda, Yumi
    Mukai, Tetsu
    [J]. BIORESEARCH OPEN ACCESS, 2020, 9 (01): : 86 - 93
  • [9] Dysregulation of Mycobacterium marinum ESX-5 Secretion by Novel 1,2,4-oxadiazoles
    Ho, Vien Q. T.
    Rong, Mark K.
    Habjan, Eva
    Bommer, Samantha D.
    Pham, Thang V.
    Piersma, Sander R.
    Bitter, Wilbert
    Ruijter, Eelco
    Speer, Alexander
    [J]. BIOMOLECULES, 2023, 13 (02)
  • [10] Mycobacterium tuberculosis Requires Regulation ESX-5 Secretion for Virulence in Irgm1-Deficient Mice
    Elliott, Sarah R.
    White, Dylan W.
    Tischler, Anna D.
    [J]. INFECTION AND IMMUNITY, 2019, 87 (02)
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