A convenient synthesis of 3-benzoylisoxazoles by 1,3-dipolar cycloaddition

被引：9

作者：

Kai, H ^{[1
]}

Tomida, M ^{[1
]}

Nakai, T ^{[1
]}

Takase, A ^{[1
]}

机构：

[1] Shionogi & Co Ltd, Discovery Res Labs, Shiga 5203423, Japan

来源：

HETEROCYCLES | 2002年 / 57卷 / 12期

关键词：

D O I：

10.3987/COM-02-9618

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient, efficient method for the preparation of 3-benzoylisoxazoles is described. Nitrile oxides generated in situ from phenylglyoxylohydroxamyl chlorides and NaHCO3 in isopropyl alcohol smoothly react with dipolarophiles at room temperature to provide the cycloadducts.

引用

页码：2299 / 2308

页数：10

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