Characterization of a novel TPMT mutation associated with azathioprine-induced myelosuppression

被引：7
|
作者：
de Beaumais, Tiphaine Adam [1 ]
Fakhoury, May [1 ]
Pigneur, Benedicte [2 ]
Viola, Sheila [2 ]
Medard, Yves [1 ]
Broly, Franck [3 ]
Jacqz-Aigrain, Evelyne [1 ]
机构：
[1] Robert Debre Hosp, Dept Paediat Pharmacol & Pharmacogenet, F-75935 Paris 19, France
[2] Trousseau Hosp, Dept Paediat Gastroenterol & Nutr, Paris, France
[3] Calmette Hosp, CHRU Lille, Biol & Pathol Ctr, UF Genopathy Pharmacotoxicogenet & Glycobiol, Lille, France
来源：
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 2009年 / 68卷 / 05期
关键词：
THIOPURINE S-METHYLTRANSFERASE; THERAPY; PHARMACOGENOMICS; DISEASE;
D O I：
10.1111/j.1365-2125.2009.03439.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：770 / 772
页数：3
相关论文
共 50 条
  • [1] Limitations of extensive TPMT genotyping in the management of azathioprine-induced myelosuppression in IBD patients
    Dewit, O.
    Moreels, T.
    Baert, F.
    Peeters, H.
    Reenaers, C.
    de Vos, M.
    Van Hootegem, Ph.
    Muls, V.
    Veereman, G.
    Mana, F.
    Van Outryve, M.
    Holvoet, J.
    Naegels, S.
    Piessevaux, H.
    Horsmans, Y.
    Gala, J. L.
    CLINICAL BIOCHEMISTRY, 2011, 44 (13) : 1062 - 1066
  • [2] Influence of TPMT polymorphisms on azathioprine-induced myelosuppression in Bangladeshi patients with systemic lupus erythematosus
    Rashid, Mohammad Mamun Ur
    Ahmed, Imtiaz
    Islam, Md. Asraful
    Tasnim, Tasnova
    Nahid, Noor Ahmed
    Apu, Mohd Nazmul Hasan
    Al-Mamun, Mir Md. Abdullah
    Islam, Md. Reazul
    Ahmed, Maizbha Uddin
    Karim, Masud
    Islam, Md. Nazrul
    Yokota, Kazushige
    Shabnaz, Samia
    Reza, Hasan Mahmud
    Islam, Mohammad Safiqul
    Hasnat, Abul
    DRUGS & THERAPY PERSPECTIVES, 2020, 36 (05) : 202 - 207
  • [3] Influence of TPMT polymorphisms on azathioprine-induced myelosuppression in Bangladeshi patients with systemic lupus erythematosus
    Mohammad Mamun Ur Rashid
    Imtiaz Ahmed
    Md. Asraful Islam
    Tasnova Tasnim
    Noor Ahmed Nahid
    Mohd Nazmul Hasan Apu
    Mir Md. Abdullah Al-Mamun
    Md. Reazul Islam
    Maizbha Uddin Ahmed
    Masud Karim
    Md. Nazrul Islam
    Kazushige Yokota
    Samia Shabnaz
    Hasan Mahmud Reza
    Mohammad Safiqul Islam
    Abul Hasnat
    Drugs & Therapy Perspectives, 2020, 36 : 202 - 207
  • [4] Azathioprine-induced fatal myelosuppression in systemic lupus erythematosus patient carrying TPMT*3C polymorphism
    Boonsrirat, U.
    Angsuthum, S.
    Vannaprasaht, S.
    Konapurivijit, J.
    Hirankarn, N.
    Tassaneeyakul, W.
    Avihingsanon, Y.
    LUPUS, 2008, 17 (02) : 132 - 134
  • [5] A REVIEW OF AZATHIOPRINE-INDUCED HEPATOTOXICITY AND MYELOSUPPRESSION IN MYASTHENIA GRAVIS
    Jack, K. L.
    Koopman, W. J.
    Hulley, D.
    Nicolle, M. W.
    MUSCLE & NERVE, 2014, 50 (04) : 719 - 719
  • [6] Impact of the Heterozygous TPMT*1/*3C Genotype on Azathioprine-Induced Myelosuppression in Kidney Transplant Recipients in Thailand
    Vannaprasaht, Suda
    Angsuthum, Susothorn
    Avihingsanon, Yingyos
    Sirivongs, Dhavee
    Pongskul, Cholatip
    Makarawate, Pattarapong
    Praditpornsilpa, Kearkiat
    Tassaneeyakul, Wongwiwat
    Tassaneeyakul, Wichittra
    CLINICAL THERAPEUTICS, 2009, 31 (07) : 1524 - 1533
  • [7] Rare gene variants in a patient with azathioprine-induced lethal myelosuppression
    Xiaoxue Yang
    Heng Xu
    Jun Yang
    Li Yang
    Annals of Hematology, 2017, 96 : 2131 - 2133
  • [8] Association of genetic variants in TPMT, ITPA, and NUDT15 with azathioprine-induced myelosuppression in southwest china patients with autoimmune hepatitis
    Miao, Qiang
    Yan, Lin
    Zhou, Yanhong
    Li, Yi
    Zou, Yuangao
    Wang, Lanlan
    Bai, Yangjuan
    Zhang, Junlong
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [9] Azathioprine-induced fatal myelosuppression in a renal-transplant recipient who carried heterozygous TPMT*1/*3C
    Tassaneeyakul, W
    Srimarthpirom, S
    Reungjui, S
    Chansung, K
    Romphurk, A
    Tassaneeyakul, W
    TRANSPLANTATION, 2003, 76 (01) : 265 - 266
  • [10] Association of genetic variants in TPMT, ITPA, and NUDT15 with azathioprine-induced myelosuppression in southwest china patients with autoimmune hepatitis
    Qiang Miao
    Lin Yan
    Yanhong Zhou
    Yi Li
    Yuangao Zou
    Lanlan Wang
    Yangjuan Bai
    Junlong Zhang
    Scientific Reports, 11
12345