Management of hidradenitis suppurativa in pregnancy

被引:27
|
作者
Perng, Powell [1 ]
Zampella, John G. [2 ]
Okoye, Ginette A. [2 ]
机构
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
[2] Johns Hopkins Univ, Dept Dermatol, Baltimore, MD 21218 USA
关键词
hidradenitis suppurativa; inflammation; inflammatory skin disease; lactation; pregnancy; post-partum; WIDE SURGICAL EXCISION; BREAST-MILK; IMMUNOSUPPRESSIVE DRUGS; ZINC SUPPLEMENTATION; SYSTEMIC THERAPIES; TREATMENT OPTIONS; RECURRENCE RATE; BIRTH-DEFECTS; CASE-SERIES; OPEN-LABEL;
D O I
10.1016/j.jaad.2016.10.032
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Hidradenitis suppurativa is a debilitating inflammatory skin disease with a chronic course and often disappointing response to treatment. Though a minority of persons (20%) reports symptom remission during pregnancy, the vast majority experiences no relief (72%), and few experience clinical deterioration (8%). Disease flares are also observed post-partum. The pathophysiological basis for pregnancy-associated fluctuations in clinical status is currently unknown. Because most women with HS require ongoing management throughout pregnancy, it is important to evaluate the suitability and safety of current treatment options for pregnant women. The following review will outline current management strategies for HS and their compatibility with pregnancy and lactation.
引用
收藏
页码:979 / 989
页数:11
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