P53 role in DNA repair and tumorigenesis

被引：0
|
作者：
Soddu, S
Sacchi, A
机构：
来源：
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH | 1997年 / 16卷 / 03期
关键词：
oncosuppressor; p53; genome stability; apoptosis; tumor progression;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The p53 oncosuppressor is the gene which has been found to be most frequently altered in human cancers. How the p53 gene contributes to tumor induction and progression is presently being investigated by numerous researchers whose specialties range from basic science to clinics. This is a brief overview of the hypotheses on p53 role in tumorigenesis and the possible use of p53 analyses in tumor prognosis and therapy.
引用
收藏
页码：237 / 242
页数：6
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