The metaphase-to-anaphase transition: avoiding a mid-life crisis

被引：43
|
作者：
CohenFix, O
Koshland, D
机构：
[1] Howard Hughes Medical Institute, Carnegie Institution of Washington, Baltimore, MD 21210
来源：
CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 06期
关键词：
D O I：
10.1016/S0955-0674(97)80080-4
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The metaphase-to-anaphase transition is a highly regulated process, which is governed by the activity of the anaphase-promoting complex (APC). The APC promotes the degradation of several proteins, including mitotic cyclins and newly identified anaphase inhibitors. Several discoveries made this year shed invaluable light on the regulation of APC activation and its substrate specificity.
引用
收藏
页码：800 / 806
页数：7
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