Insights into biomolecular function from small-angle scattering

被引：41
|
作者：
Trewhella, J
机构：
[1] Chem. Sci. and Technology Division, Mail Stop G758, Los Alamos Natl. L., Los Alamos
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 05期
关键词：
D O I：
10.1016/S0959-440X(97)80081-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent advances in neutron and X-ray sources and instrumentation, new and improved scattering techniques, and molecular biology techniques, which have permitted facile preparation of samples, have each led to new opportunities in using small-angle scattering to study the conformations and interactions of biological macromolecules in solution as a function of their properties. For example, new instrumentation on synchrotron sources has facilitated time-resolved studies that yield insights into protein folding. More powerful neutron sources, combined with molecular biology tools that isotopically label samples, have facilitated studies of biomolecular interactions, including those involving active enzymes. (C) Current Biology Ltd ISSN 0959-440X
引用
收藏
页码：702 / 708
页数：7
相关论文
共 50 条
12345