SPATIAL STABILITY OF PARTICLES TRAPPED BY TIME-DIVISION OPTICAL TWEEZERS

被引:6
|
作者
Yamamoto, Johtaro [1 ]
Iwai, Toshiaki [1 ]
机构
[1] Tokyo Univ Agr & Technol, Grad Sch Bioapplicat & Syst Engn, Koganei, Tokyo 1848588, Japan
关键词
Brownian motion; gradient force; optical tweezers; Rayleigh scattering approximation; Smoluchowski equation; COMPUTER-GENERATED HOLOGRAMS; GAUSSIAN-BEAM; CELL; FORCES;
D O I
10.1080/15599610903391168
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
We developed an on-demand multiple-spot holographic optical tweezers (HOT) system based on quasi-simultaneous generation of two intensity-spot patterns by alternately sending the two corresponding hologram patterns to a spatial light modulator. This switching operation reduces the spatial stability of a Brownian particle trapped inside the generated intensity spot. In this study, numerical analysis of the conditions for stable particle trapping in the time-division HOT is conducted using the Smoluchowski equation under the Rayleigh scattering approximation. The relationship between the particle size, the switching rate, and the focused laser beam power is obtained. Experiments confirm the validity of the numerical analysis.
引用
收藏
页码:253 / 263
页数:11
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