Topical corticosteroids in psoriasis: strategies for improving safety

被引:56
|
作者
Horn, E. J. [5 ]
Domm, S. [4 ]
Katz, H. I. [3 ]
Lebwohl, M. [2 ]
Mrowietz, U. [4 ]
Kragballe, K. [1 ]
机构
[1] Arhus Univ Hosp, Dept Dermatol, Aarhus, Denmark
[2] Mt Sinai Sch Med, Dept Dermatol, New York, NY USA
[3] Univ Minnesota, Dept Dermatol, Minneapolis, MN 55455 USA
[4] Univ Med Ctr Schleswig Holstein, Dept Dermatol, Psoriasis Ctr, Kiel, Germany
[5] Int Psoriasis Council, Dallas, TX USA
关键词
corticosteroids; psoriasis; safety; topical therapy; FLUTICASONE PROPIONATE OINTMENT; GLUCOCORTICOID-RECEPTOR; LIMITED APPLICATION; DOUBLE-BLIND; BETAMETHASONE DIPROPIONATE; HALOBETASOL PROPIONATE; CALCIPOTRIENE OINTMENT; MAINTENANCE TREATMENT; MULTICENTER TRIAL; EFFICACY;
D O I
10.1111/j.1468-3083.2009.03358.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Corticosteroids are a mainstay of topical therapy for psoriasis. While efficacious and relatively safe when used carefully, the potential for side effects, notably skin atrophy and adrenal suppression, have been associated with excesses in potency, prolonged or widespread use. The International Psoriasis Council Working Group on Topical Therapy has reviewed the efficacy and safety of topical corticosteroids and recommends strategies for safe, long-term use of these agents.
引用
收藏
页码:119 / 124
页数:6
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