Natural-abundance 15N-13C correlation spectra of vitamin B-12

被引：17
|
作者：
Kupce, Eriks
Freeman, Ray [1 ]
机构：
[1] Univ Cambridge Jesus College, Cambridge CB5 8BL, England
[2] Varian Ltd, Oxford, England
来源：
MAGNETIC RESONANCE IN CHEMISTRY | 2007年 / 45卷 / 02期
关键词：
NMR; correlation spectroscopy; natural-abundance N-15 and C-13; reconstruction; sensitivity; vitamin B-12;
D O I：
10.1002/mrc.1947
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two-dimensional nitrogen-carbon NMR correlation spectra have been derived by a new reconstruction technique based on standard two-dimensional HMQC and HMBC spectra, and operating with natural N-15 and C-13 isotopic abundances. Compared with conventional three-dimensional spectroscopy in which N-15 and C-13 spins must be present in the same molecule, the reconstruction method offers two orders of magnitude improvement in sensitivity. Vitamin B-12 serves as an illustrative example. Copyright (c) 2007 John Wiley & Sons, Ltd.
引用
收藏
页码：103 / 105
页数：3
相关论文
共 50 条
12345