In vitro effects of synthetic muscimol and an extract from Amanita muscaria on human recombinant MAOB enzyme

被引：2
|
作者：
Voynova, Maria [1 ]
Shkondrov, Aleksandar [2 ]
Krasteva, Ilina [2 ]
Kondeva-Burdina, Magdalena [1 ]
机构：
[1] Med Univ Sofia, Fac Pharm, Dept Pharmacol Pharmacotherapy & Toxicol, Lab Drug Metab & Drug Tox, 2 Dunav St, Sofia 1000, Bulgaria
[2] Med Univ Sofia, Fac Pharm, Dept Pharmacognosy, 2 Dunav St, Sofia 1000, Bulgaria
来源：
PHARMACIA | 2021年 / 68卷 / 01期
关键词：
Amanita muscaria; muscimol; MAOB enzyme; MONOAMINE-OXIDASE; SELEGILINE; INHIBITORS;
D O I：
10.3897/pharmacia.68.e60705
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The effects of synthetic muscimol and an extract from Amanita muscaria, containing this compound on the activity of human recombinant MAOB enzyme (hMAOB) were studied. Muscimol had statistically significant inducing effect on hMAOB at concentrations 0.25-5 mu M, while A. muscaria extract did not influence the enzyme activity at all.
引用
收藏
页码：147 / 150
页数：4
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