Characteristics of Nanocrystalline Diamond Films on Titanium Surface and its Impact on the Proliferation and Adhesion of Cells

被引:5
|
作者
Ma, Shanshan [1 ,3 ]
Liu, Junsong [2 ]
Luo, Wenjing [1 ]
Zhang, Hongyi [1 ]
Meng, Xing [1 ]
Guo, Yu [1 ]
Cheng, Shaoheng [2 ]
Wang, Qiliang [2 ]
Zhou, Yanmin [1 ]
Li, Hongdong [2 ]
机构
[1] Jilin Univ, Sch & Hosp Stomatol, Dept Dent Implantol, Changchun 130021, Peoples R China
[2] Jilin Univ, State Key Lab Superhard Mat, Changchun 130012, Peoples R China
[3] Jilin Prov Key Lab Tooth Dev & Bone Remodeling, Changchun, Peoples R China
基金
中国国家自然科学基金;
关键词
Nanocrystalline diamond films (NCD); Adhesion; Cytotoxocity; Proliferation;
D O I
10.2485/jhtb.25.6
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Nanocrystalline diamond has extensive application in biology modified material aspects of human implants, because it has good mechanical properties such as corrosion resistance and biocompatibility. This study investigated the surface characteristics and biocompatibility of pure titanium whose surface was modified with nanocrystalline diamond by Microwave Plasma Chemical Vapor Deposition. Scanning electron microscope (SEM), Spectruman analysis ray diffraction and X-Ray photoelectron spectroscopy were used to analyze the chemical composition and surface topography of nanocrystalline diamond. We found that the particle size of the diamond on the titanium disc is nanocrystalline, and is without impure elements. In the experiment, we used Human Osteoblast-like cells MG63 to investigate the bioactivity of nanocrystalline diamond film. The attachment and proliferation of the cells were tested by NAPI, CCK-8. The result showed that oxygen terminated NCD groups had a significant advantage compared with hydrogen terminated and titanium groups on attachment and proliferation of MG63.
引用
收藏
页码:6 / 14
页数:9
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