Cu(OAc)2 catalyzed Sonogashira cross-coupling reaction in amines

被引:25
|
作者
Guo, Sheng Mei [1 ]
Deng, Chen Liang [1 ]
Li, Jin Heng [1 ]
机构
[1] Hunan Normal Univ, Coll Chem & Chem Engn, Minist Educ, Key Lab Chem Biol & Tradit Chinese Med Res, Changsha 410081, Peoples R China
基金
中国国家自然科学基金;
关键词
Cu(OAc)(2); Sonogashira cross-coupling reaction; aryl halide; alkyne;
D O I
10.1016/j.cclet.2006.11.019
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple Cu(OAc)(2) catalyzed Sonogashira coupling protocol is presented. It was found that the couplings of a variety of aryl halides with terminal alkynes were conducted smoothly to afford the corresponding desired products in moderate to excellent yields, using Cu(OAc)(2) as the catalyst and Et3N as the solvent. (c) 2006 Jin Heng Li. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码:13 / 16
页数:4
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