A Few Good Commensals: Gut Microbes Use IFN-γ to Fight Salmonella

被引：12

作者：

Ost, Kyla S. ^{[1
]}

Round, June L. ^{[1
]}

机构：

[1] Univ Utah, Dept Pathol, Div Microbiol & Immunol, Salt Lake City, UT 84112 USA

来源：

IMMUNITY | 2017年 / 46卷 / 06期

关键词：

BACTERIA; INFECTION;

D O I：

10.1016/j.immuni.2017.06.010

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Whereas strong evidence supports the notion that the microbiota promotes immune system maturation in multiple tissues, the identity of the specific microbes that elicit protective immunity to different infections is less clear. In a recent issue of Cell Host & Microbe, Thiemann et al. (2017) report the identification of specific gut bacteria that protect from Salmonella infection by priming host IFN-gamma responses.

引用

页码：977 / 979

页数：3

共 2 条

[1] IFN-γ Hinders Recovery from Mucosal Inflammation during Antibiotic Therapy for Salmonella Gut Infection
Dolowschiak, Tamas
Mueller, Anna Angelika
Pisan, Lynn Joanna
Feigelman, Rounak
Felmy, Boas
Sellin, Mikael Erik
Namineni, Sukumar
Bidong Dinh Nguyen
Wotzka, Sandra Yvonne
Heikenwalder, Mathias
von Mering, Christian
Mueller, Christoph
Hardt, Wolf-Dietrich
[J]. CELL HOST & MICROBE, 2016, 20 (02) : 238 - 249
[2] The Gut Microbiota Reduces Colonization of the Mesenteric Lymph Nodes and IL-12-Independent IFN-γ Production During Salmonella Infection
Fernandez-Santoscoy, Maria
Wenzel, Ulf A.
Yrlid, Ulf
Cardell, Susanna
Backhed, Fredrik
Wick, Mary Jo
[J]. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2015, 5

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