Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients: population-based longitudinal study

被引:111
|
作者
Hawley, Samuel [1 ]
Javaid, M. Kassim [1 ,2 ]
Prieto-Alhambra, Daniel [1 ,2 ,3 ,4 ,5 ]
Lippett, Janet [6 ]
Sheard, Sally [1 ]
Arden, Nigel K. [1 ,2 ]
Cooper, Cyrus [1 ,2 ]
Judge, Andrew [1 ,2 ]
机构
[1] Univ Oxford, Oxford NIHR Musculoskeletal Biomed Res Unit, Oxford, England
[2] Univ Southampton, MRC, Lifecourse Epidemiol Unit, Southampton, Hants, England
[3] Univ Autonoma Barcelona, Hosp del Mar Med Res Inst IMIM, E-08193 Barcelona, Spain
[4] Inst Salud Carlos III, RETICEF, Barcelona, Spain
[5] Univ Autonoma Barcelona, IDIAP Jordi Gol Primary Care Res Inst, GREMPAL Res Grp, E-08193 Barcelona, Spain
[6] Royal Berkshire NHS Fdn Trust, Reading, Berks, England
基金
美国国家卫生研究院;
关键词
epidemiology; hip fracture; fracture liaison service; orthogeriatrician; osteoporosis; older people; OLDER PATIENTS; MORTALITY; MANAGEMENT; PREVENTION; GUIDELINE; OUTCOMES; WOMEN; RISK;
D O I
10.1093/ageing/afv204
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Setting: Hospital Episode Statistics database linked to Office for National Statistics mortality records for 11 acute hospitals in a region of England. Population: patients aged over 60 years admitted for a primary hip fracture from 2003 to 2013. Methods: each hospital was analysed separately and acted as its own control in a before-after time-series design in which the appointment of an orthogeriatrician or set-up/expansion of an FLS was evaluated. Multivariable Cox regression (mortality) and competing risk survival models (second hip fracture) were used. Fixed effects meta-analysis was used to pool estimates of impact for interventions of the same type. Results: of 33,152 primary hip fracture patients, 1,288 sustained a second hip fracture within 2 years (age and sex standardised proportion of 4.2%). 3,033 primary hip fracture patients died within 30 days and 9,662 died within 1 year (age and sex standardised proportion of 9.5% and 29.8%, respectively). The estimated impact of introducing an orthogeriatrician on 30-day and 1-year mortality was hazard ratio (HR) = 0.73 (95% CI: 0.65-0.82) and HR = 0.81 (CI: 0.75-0.87), respectively. Following an FLS, these associations were as follows: HR = 0.80 (95% CI: 0.71-0.91) and HR = 0.84 (0.77-0.93). There was no significant impact on time to second hip fracture. Conclusions: the introduction and/or expansion of orthogeriatric and FLS models of post-hip fracture care has a beneficial effect on subsequent mortality. No evidence for a reduction in second hip fracture rate was found.
引用
收藏
页码:236 / 242
页数:7
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