Laboratory Evaluation of a Dual-Path Platform Assay for Rapid Point-of-Care HIV and Syphilis Testing

被引：21
|
作者：
Leon, S. R. [1 ,2 ]
Ramos, L. B. [1 ]
Vargas, S. K. [1 ]
Kojima, N. [3 ]
Perez, D. G. [1 ,4 ]
Caceres, C. F. [1 ]
Klausner, J. D. [5 ]
机构：
[1] Univ Peruana Cayetano Heredia, Lab Sexual Hlth, Lima, Peru
[2] Direcc Invest Socios Salud Sucursal Peru, Lima, Peru
[3] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA
[4] Natl Hosp Daniel A Carrion, Dept Clin Pathol, Callao, Peru
[5] Univ Calif Los Angeles, David Geffen Sch Med, Dept Med, Div Infect Dis, Los Angeles, CA 90095 USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2016年 / 54卷 / 02期
基金：
美国国家卫生研究院;
关键词：
SEROPREVALENCE; PERU; SEX;
D O I：
10.1128/JCM.03152-15
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We assessed the laboratory performance of the Chembio dual-path platform HIV-syphilis rapid immunodiagnostic test and electronic reader for detection of HIV and Treponema pallidum antibodies in 450 previously characterized serum specimens. For visual or electronic reader HIV antibody detection, the sensitivity was 100% and the specificity was 98.7%. For visual T. pallidum antibody detection, the test sensitivity was 94.7% and the specificity was 100.0%; with the electronic reader, the sensitivity was 94.7% and the specificity was 99.7%.
引用
收藏
页码：492 / 494
页数：3
相关论文
共 50 条
  • [1] Laboratory evaluation of the Chembio Dual Path Platform HIV-Syphilis Assay
    Kalou, Mireille B.
    Castro, Arnold
    Watson, Amy
    Jost, Heather
    Clay, Stacy
    Tun, Ye
    Chen, Cheng
    Karem, Kevin
    Nkengasong, John N.
    Ballard, Ronald
    Parekh, Bharat
    [J]. AFRICAN JOURNAL OF LABORATORY MEDICINE, 2016, 5 (01)
  • [2] Multisite Laboratory Evaluation of a Dual Human Immunodeficiency Virus (HIV)/Syphilis Point-of-Care Rapid Test for Simultaneous Detection of HIV and Syphilis Infection
    Bristow, Claire C.
    Adu-Sarkodie, Yaw
    Ondondo, Raphael O.
    Bukusi, Elizabeth Anne
    Dagnra, Claver Anoumou
    Oo, Khin Yi
    Pe, Eh Htoo
    Khamsay, Chanthavysouk
    Houng, Le Thi
    Campuzano, Roberto Vazquez
    Estes, Jason
    Klausner, Jeffrey D.
    [J]. OPEN FORUM INFECTIOUS DISEASES, 2014, 1 (01):
  • [3] Accuracy of a Dual Path Platform (DPP) Assay for the Rapid Point-of-Care Diagnosis of Human Leptospirosis
    Nabity, Scott A.
    Ribeiro, Guilherme S.
    Aquino, Carolina Lessa
    Takahashi, Daniele
    Damiao, Alcineia Oliveira
    Goncalves, Andre H. O.
    Miranda-Filho, Democrito B.
    Greenwald, Rena
    Esfandiari, Javan
    Lyashchenko, Konstantin P.
    Reis, Mitermayer G.
    Medeiros, Marco A.
    Ko, Albert I.
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2012, 6 (11):
  • [4] MULTI-SITE LABORATORY EVALUATION OF THE SD BIOLINE DUO HIV/SYPHILIS DUAL POINT-OF-CARE RAPID TEST
    Bristow, Claire C.
    Adu-Sarkodie, Yaw
    Ondondo, Raphael
    Bukusi, Elizabeth Anne
    Dagnra, Anoumou
    Oo, Khin Yi
    Khamsay, Chanthavysouk
    Huong, Le Thi
    Campuzano, Roberto Vazquez
    Klausner, Jeffrey
    [J]. SEXUALLY TRANSMITTED DISEASES, 2014, 41 : S79 - S79
  • [5] A Laboratory-Based Evaluation of Four Rapid Point-of-Care Tests for Syphilis
    Causer, Louise M.
    Kaldor, John M.
    Fairley, Christopher K.
    Donovan, Basil
    Karapanagiotidis, Theo
    Leslie, David E.
    Robertson, Peter W.
    McNulty, Anna M.
    Anderson, David
    Wand, Handan
    Conway, Damian P.
    Denham, Ian
    Ryan, Claire
    Guy, Rebecca J.
    [J]. PLOS ONE, 2014, 9 (03):
  • [6] Evaluation of the Dual Path Platform syphilis point of care test in North Queensland
    Skinner, Linsey
    Robertson, Gemma
    Norton, Robert
    [J]. PATHOLOGY, 2015, 47 (07) : 718 - 720
  • [7] Field evaluation of a smartphone-based electronic reader of rapid dual HIV and syphilis point-of-care immunoassays
    Allan-Blitz, Lao-Tzu
    Vargas, Silver K.
    Konda, Kelika A.
    Herbst de Cortina, Sasha
    Caceres, Carlos F.
    Klausner, Jeffrey D.
    [J]. SEXUALLY TRANSMITTED INFECTIONS, 2018, 94 (08) : 589 - 593
  • [8] EVALUATION OF FIVE RAPID POINT-OF-CARE TESTS FOR SYPHILIS: TWO TREPONEMAL ONLY, AND THREE DUAL TREPONEMAL/HIV ASSAYS
    Fakile, Y.
    Hoover, K.
    Delaney, K.
    Wesolowski, L.
    Asef, C.
    Sun, Y.
    Park, I.
    Chow, J.
    Schapiro, J.
    Novak, S.
    Philip, S.
    Karem, K.
    [J]. SEXUALLY TRANSMITTED INFECTIONS, 2015, 91 : A29 - A29
  • [9] Point-of-care Laboratory Testing
    Gauglitz, Guenter
    Luppa, Peter B.
    [J]. CHEMIE IN UNSERER ZEIT, 2009, 43 (05) : 308 - 318
  • [10] Prospective evaluation of accuracy and clinical utility of the Dual Path Platform (DPP) assay for the point-of-care diagnosis of leptospirosis in hospitalized patients
    Nabity, Scott A.
    Hagan, Jose E.
    Araujo, Guilherme
    Damiao, Alcineia O.
    Cruz, Jaqueline S.
    Nery, Nivison
    Wunder, Elsio A., Jr.
    Reis, Mitermayer G.
    Ko, Albert I.
    Ribeiro, Guilherme S.
    [J]. PLOS NEGLECTED TROPICAL DISEASES, 2018, 12 (02):
12345