Cognitive effects of creatine ethyl ester supplementation

被引：29

作者：

Ling, Jonathan ^{[1
]}

Kritikos, Minos ^{[2
]}

Tiplady, Brian ^{[3
]}

机构：

[1] Univ Sunderland, Dept Pharm Hlth & Well Being, Sunderland SR1 3SD, England

[2] Univ Bristol, Sch Med Sci, Bristol BS8 1TD, Avon, England

[3] Univ Edinburgh, Div Anaesthesia Crit Care & Pain Med, Edinburgh, Midlothian, Scotland

来源：

BEHAVIOURAL PHARMACOLOGY | 2009年 / 20卷 / 08期

关键词：

creatine ethyl ester; creatine monohydrate; human; intelligence; memory; oral supplementation; reaction time; ORAL CREATINE; INBORN ERROR; DEFICIENCY; DISEASE; BRAIN; MONOHYDRATE; METABOLISM; PHARMACOKINETICS; THERAPY; HEALTH;

D O I：

10.1097/FBP.0b013e3283323c2a

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Supplementation with creatine-based substances as a means of enhancing athletic performance has become widespread. Until recently, however, the effects of creatine supplementation on cognitive performance has been given little attention. This study used a new form of creatine - creatine ethyl ester - to investigate whether supplementation would improve performance in five cognitive tasks, using a double-blind, placebo-controlled study. Creatine dosing led to an improvement over the placebo condition on several measures. Although creatine seems to facilitate cognition on some tasks, these results require replication using objective measures of compliance. The improvement is discussed in the context of research examining the influence of brain energy capacity on cognitive performance. Behavioural Pharmacology 20:673-679 (C) 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins.

引用

页码：673 / 679

页数：7

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