3D Bioprinting of In Vitro Models Using Hydrogel-Based Bioinks

被引:48
|
作者
Choi, Yeong-Jin [1 ]
Park, Honghyun [1 ]
Ha, Dong-Heon [2 ]
Yun, Hui-Suk [1 ]
Yi, Hee-Gyeong [3 ]
Lee, Hyungseok [4 ,5 ]
机构
[1] Korea Inst Mat Sci KIMS, Dept Adv Biomat Res, Chang Won 51508, South Korea
[2] EDmicBio Inc, Seoul 02445, South Korea
[3] Chonnam Natl Univ CNU, Coll Agr & Life Sci, Dept Rural & Biosystems Engn, Gwangju 61186, South Korea
[4] Kangwon Natl Univ KNU, Dept Mech & Biomed Engn, Chunchon 24341, South Korea
[5] Kangwon Natl Univ KNU, Interdisciplinary Program Biohlth Machinery Conve, Chunchon 24341, South Korea
基金
新加坡国家研究基金会;
关键词
3D bioprinting; in vitro model; hydrogel; bioink; 3D cell printing; tissue engineering;
D O I
10.3390/polym13030366
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Coronavirus disease 2019 (COVID-19), which has recently emerged as a global pandemic, has caused a serious economic crisis due to the social disconnection and physical distancing in human society. To rapidly respond to the emergence of new diseases, a reliable in vitro model needs to be established expeditiously for the identification of appropriate therapeutic agents. Such models can be of great help in validating the pathological behavior of pathogens and therapeutic agents. Recently, in vitro models representing human organs and tissues and biological functions have been developed based on high-precision 3D bioprinting. In this paper, we delineate an in-depth assessment of the recently developed 3D bioprinting technology and bioinks. In particular, we discuss the latest achievements and future aspects of the use of 3D bioprinting for in vitro modeling.
引用
收藏
页码:1 / 18
页数:18
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