Synthesis and biological activities of 2'-modified 4'-thionucleosides

被引:10
|
作者
Yoshimura, Y [1 ]
Kitano, K [1 ]
Watanabe, M [1 ]
Satoh, H [1 ]
Sakata, S [1 ]
Miura, S [1 ]
Ashida, N [1 ]
Machida, H [1 ]
Matsuda, A [1 ]
机构
[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,KITA KU,SAPPORO,HOKKAIDO 060,JAPAN
来源
NUCLEOSIDES & NUCLEOTIDES | 1997年 / 16卷 / 7-9期
关键词
D O I
10.1080/07328319708006142
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We have synthesized 4'-thioDMDC, 4'-thiogemcitabine, and 4'-thioarabinonucleosides, as potential antitumor and antiviral agents, originated from D-glucose. Biological activities of these compounds are also described.
引用
收藏
页码:1103 / 1106
页数:4
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