Interaction of non-alcoholic fatty liver disease with other liver diseases

被引:48
|
作者
Clouston, AD
Powell, EE
机构
[1] Princess Alexandra Hosp, Dept Gastroenterol & Hepatol, Brisbane, Qld 4102, Australia
[2] Univ Queensland, Brisbane, Qld 4067, Australia
[3] Sullivan Nicolaides Pathol, Brisbane, Qld, Australia
关键词
co-factor; non-alcoholic steatohepatitis; weight reduction; hepatitis C; alcohol; orthotopic liver transplantation;
D O I
10.1053/bega.2002.0329
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Obesity-related steatosis is an increasingly common histological finding in liver biopsies and may co-exist with other chronic liver diseases. Although non-alcoholic fatty liver disease (NAFLD) without true steatohepatitis is generally a benign condition, when another liver disease is present, steatosis may exacerbate the liver damage. In this review, we discuss the interaction of obesity-related steatosis with chronic hepatitis C, alcoholic liver disease, disorders of hepatic iron storage and drug-induced liver disease. The role of weight reduction in minimizing liver injury in patients with chronic hepatitis C is discussed. Finally, we discuss the problems associated with orthotopic liver transplantation for patients with NAFLD.
引用
收藏
页码:767 / 781
页数:15
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