Chilblain-like leukemia cutis

被引:8
|
作者
Affleck, Andrew G. [1 ]
Ravenscroft, Jane C.
Leach, Iain H.
机构
[1] Univ Hosp Nottingham NHS Trust, Queens Med Ctr, Dept Dermatol, Nottingham NG7 2UH, England
[2] Univ Hosp Nottingham NHS Trust, Queens Med Ctr, Dept Histopathol, Nottingham NG7 2UH, England
关键词
D O I
10.1111/j.1525-1470.2007.00330.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We present a 6-year-old girl with an 8-month history of fluctuating chilblain-like lesions on the toes. A full blood count showed slight thrombocytopenia and monocytosis. A skin biopsy specimen showed a dense perivascular and superficial dermal cellular infiltrate which was CD3(-), CD43(+), and lysosyme + on immunocytochemistry, suggesting a monocytic origin. Juvenile myelomonocytic leukemia was diagnosed after a bone marrow biopsy and spontaneous marrow colony growth in culture.
引用
收藏
页码:38 / 41
页数:4
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