Autism Detection in Children by Combined Use of Gaze Preference and the M-CHAT-R in a Resource-Scarce Setting

被引：6

作者：

Jensen, Kelly ^{[1
,2
,13
]}

Noazin, Sassan ^{[3
]}

Bitterfeld, Leandra ^{[4
,14
]}

Carcelen, Andrea ^{[3
]}

Vargas-Cuentas, Natalia, I ^{[5
]}

Hidalgo, Daniela ^{[5
,6
]}

Valenzuela, Alejandra ^{[5
]}

Roman-Gonzalez, Avid ^{[5
]}

Krebs, Casey ^{[7
]}

Clement, Vincent ^{[6
]}

Nolan, Cody ^{[8
]}

Barrientos, Franklin ^{[5
]}

Mendoza, Ardi Knobel ^{[9
]}

Noriega-Donis, Paola ^{[10
]}

Palacios, Claudia ^{[5
]}

Ramirez, Andrea ^{[5
]}

Vittet, Macarena ^{[5
]}

Hafeez, Emil ^{[3
]}

Torres-Viso, Mariana ^{[11
]}

Velarde, Myriam ^{[12
]}

Moulton, Lawrence H. ^{[3
]}

Powers, Michael D. ^{[7
,11
]}

Gilman, Robert H. ^{[3
]}

Zimic, Mirko ^{[5
]}

机构：

[1] Tulane Univ, Sch Med, 1430 Tulane Ave, New Orleans, LA 70112 USA

[2] Tulane Univ, Sch Publ Hlth & Trop Med, New Orleans, LA USA

[3] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Int Hlth, Baltimore, MD 21205 USA

[4] Johns Hopkins Univ, Sch Nursing, Baltimore, MD USA

[5] Univ Peruana Cayetano Heredia, Sci & Philosophy Fac, Bioinformat & Mol Biol Lab, Res & Dev Lab, Lima, Peru

[6] Univ Peruana Cayetano Heredia, Psychol Fac, Lima, Peru

[7] Yale Univ, Sch Med, Yale Child Study Ctr, New Haven, CT USA

[8] Weill Cornell Med Coll, New York, NY USA

[9] Rutgers Robert Wood Johnson Med Sch, New Brunswick, NJ USA

[10] Johns Hopkins Univ, Whiting Sch Engn, Baltimore, MD USA

[11] CCSN Ctr Children Special Needs, Glastonbury, CT USA

[12] IMLA Inst Med Lengua Aprendazaje, Lima, Peru

[13] Louisiana State Univ, Baton Rouge, LA 70803 USA

[14] USA Indian Hlth Serv, Albuquerque, NM USA

来源：

JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2021年 / 51卷 / 03期

关键词：

Autism spectrum disorder; Developmental disorder; Eye tracking; Gaze preference; ASD diagnosis; SOCIAL ATTENTION; SPECTRUM;

D O I：

10.1007/s10803-021-04878-0

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

Most children with autism spectrum disorder (ASD), in resource-limited settings (RLS), are diagnosed after the age of four. Our work confirmed and extended results of Pierce that eye tracking could discriminate between typically developing (TD) children and those with ASD. We demonstrated the initial 15 s was at least as discriminating as the entire video. We evaluated the GP-MCHAT-R, which combines the first 15 s of manually-coded gaze preference (GP) video with M-CHAT-R results on 73 TD children and 28 children with ASD, 36-99 months of age. The GP-MCHAT-R (AUC = 0.89 (95%CI: 0.82-0.95)), performed significantly better than the MCHAT-R (AUC = 0.78 (95%CI: 0.71-0.85)) and gaze preference (AUC = 0.76 (95%CI: 0.64-0.88)) alone. This tool may enable early screening for ASD in RLS.

引用

页码：994 / 1006

页数：13

共 9 条

[1] Autism Detection in Children by Combined Use of Gaze Preference and the M-CHAT-R in a Resource-Scarce Setting
Kelly Jensen
Sassan Noazin
Leandra Bitterfeld
Andrea Carcelen
Natalia I. Vargas-Cuentas
Daniela Hidalgo
Alejandra Valenzuela
Avid Roman-Gonzalez
Casey Krebs
Vincent Clement
Cody Nolan
Franklin Barrientos
Ardi Knobel Mendoza
Paola Noriega-Donis
Claudia Palacios
Andrea Ramirez
Macarena Vittet
Emil Hafeez
Mariana Torres-Viso
Myriam Velarde
Lawrence H. Moulton
Michael D. Powers
Robert H. Gilman
Mirko Zimic
Journal of Autism and Developmental Disorders, 2021, 51 : 994 - 1006
[2] M-CHAT-R/F Validation as a screening tool for early detection in children with autism spectrum disorder
Elisa Coelho-Mcdeiros, Maria
Bronstein, Jonathan
Aedo, Karim
Pereira, Jaime A.
Arrano, Veronica
Perez, Carolina A.
Valenzuela, Patricia M.
Moore, Rosario
Garrido, Isabel
Bedregal, Paula
REVISTA CHILENA DE PEDIATRIA-CHILE, 2019, 90 (05): : 492 - 499
[3] Sociodemographic Barriers to Early Detection of Autism: Screening and Evaluation Using the M-CHAT, M-CHAT-R, and Follow-Up
Khowaja, Meena K.
Hazzard, Ann P.
Robins, Diana L.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS, 2015, 45 (06) : 1797 - 1808
[4] Sociodemographic Barriers to Early Detection of Autism: Screening and Evaluation Using the M-CHAT, M-CHAT-R, and Follow-Up
Meena K. Khowaja
Ann P. Hazzard
Diana L. Robins
Journal of Autism and Developmental Disorders, 2015, 45 : 1797 - 1808
[5] Maternal and birth risk factors for children screening positive for autism spectrum disorders on M-CHAT-R
Ravi, Saranya
Chandrasekaran, Venkatesh
Kattimani, Shivanand
Subramanian, Mahadevan
ASIAN JOURNAL OF PSYCHIATRY, 2016, 22 : 17 - 21
[6] Modified Checklist for Autism in Toddlers, Revised, with Follow-Up (M-CHAT-R/F) and Language Development in Extremely Preterm Children
Wilaisakditipakorn, Tanaporn J.
Anderson, Stephanie
JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS, 2018, 39 (02): : S6 - S7
[7] Autism spectrum disorder screening in children aged 16-30 months using the Modified Checklist for Autism in Toddlers-Revised (M-CHAT-R)
Aditya, Clarissa J.
Dahliana, Jenni K.
Widodo, Ariani D.
Sekartini, Rini
PAEDIATRICA INDONESIANA, 2021, 61 (05) : 247 - 252
[8] Indonesian Modified Checklist for Autism in Toddler, Revised with Follow-Up (M-CHAT-R/F) for Autism Screening in Children at Sanglah General Hospital, Bali-Indonesia
Windiani, I. Gusti Trisna
Soetjiningsih
Adnyana, I. Gusti Agung Sugitha
Lestari, Kadek Apik
BALI MEDICAL JOURNAL, 2016, 5 (02) : 133 - 137
[9] Validation of the Hindi Versions of Three Autism Specific Screening Tools (M-CHAT-R/F, RBSK-ASQ and TABC) Widely Used in India in 16-30-Month-Old Children
Mukherjee, Sharmila B.
Manivannan, Dhanasangari
Sharma, Suvasini
INDIAN PEDIATRICS, 2024, 61 (04) : 323 - 329

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