Could secondary prevention of coronary heart disease be more effective?

被引:0
|
作者
Makolkin, V. I. [1 ]
机构
[1] IM Sechenov Moscow Med Acad, Moscow, Russia
来源
关键词
Coronary heart disease; secondary prevention; beta-adrenoblockers; ivabradine; VENTRICULAR SYSTOLIC DYSFUNCTION; SUBGROUP ANALYSIS; ARTERY-DISEASE; BEAUTIFUL; ANGINA; TRIAL;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Beta-adrenoblockers (BAB) in secondary prevention of coronary heart disease (CH D) are not always effective, due to non-achieved target heart rate (HR). The reasons for that could include medication intolerance, baseline bradycardia (HR<55bpm), II-III Stage atrio-ventricular blocks, and acute episodes of generalized weakness when HR is reduced. In these situations, BAB could be effectively combined with ivabradine (10-15 mg/d). This combination provides an opportunity to achieve target HR levels (60-55 bpm).
引用
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页码:92 / 96
页数:5
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