Proteases in Fas-mediated apoptosis

被引：0
|
作者：
Zhivotovsky, B [1 ]
Burgess, DH [1 ]
Schlegel, J [1 ]
Porn, MI [1 ]
Vanags, D [1 ]
Orrenius, S [1 ]
机构：
[1] KAROLINSKA INST,DIV TOXICOL,INST ENVIRONM MED,S-17177 STOCKHOLM,SWEDEN
来源：
JOURNAL OF CELLULAR BIOCHEMISTRY | 1997年 / 64卷 / 01期
关键词：
apoptosis; Fas; proteases; substrates;
D O I：
10.1002/(SICI)1097-4644(199701)64:1<43::AID-JCB7>3.3.CO;2-S
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Involvement of a unique family of cysteine proteases in the multistep apoptotic process has been documented. Cloning of several mammalian genes identifies some components of this cellular response. However, it is currently unclear which protease plays a role as a signal and/or effector of apoptosis. We summarize contributions to the data concerning proteases in Fas-mediated apoptosis. (C) 1997 Wiley-Liss, Inc.
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收藏
页码：43 / 49
页数：7
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