PyBoolNet: a python']python package for the generation, analysis and visualization of boolean networks

被引:56
|
作者
Klarner, Hannes [1 ]
Streck, Adam [1 ]
Siebert, Heike [1 ]
机构
[1] Free Univ Berlin, Inst Math, D-14195 Berlin, Germany
关键词
REGULATORY NETWORKS;
D O I
10.1093/bioinformatics/btw682
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Motivation: The goal of this project is to provide a simple interface to working with Boolean networks. Emphasis is put on easy access to a large number of common tasks including the generation and manipulation of networks, attractor and basin computation, model checking and trap space computation, execution of established graph algorithms as well as graph drawing and layouts. Results: PYBOOLNET is a Python package for working with Boolean networks that supports simple access to model checking via NUSMV, standard graph algorithms via NETWORKX and visualization via DOT. In addition, state of the art attractor computation exploiting POTASSCO ASP is implemented. The package is function-based and uses only native Python and NETWORKX data types. Availability and Implementation: https://github. com/hklarner/PyBoolNet Contact: hannes. klarner@fu-berlin.de
引用
收藏
页码:770 / 772
页数:3
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