Early administration of anti-mesothelin antibody inhibits liver metastasis of pancreatic cancer in xenograft mouse model

被引：0
|
作者：
Fujii, Yuki [1 ]
Kamachi, Hirofumi [1 ]
Fukai, Moto [1 ]
Orimo, Tatsuya [1 ]
Sakamoto, Yuzuru [1 ]
Asahi, Yoh [1 ]
Nagatsu, Akihisa [1 ]
Shimada, Shingo [1 ]
Kakisaka, Tatsuhiko [1 ]
Kamiyama, Toshiya [2 ]
Taketomi, Akinobu [2 ]
机构：
[1] Hokkaido Univ, Grad Sch, Dept Gastroenterol Surg 1, Sapporo, Hokkaido, Japan
[2] Hokkaido Univ, Grad Sch Med, Dept Gastroenterol Surg 1, Sapporo, Hokkaido, Japan
来源：
CANCER SCIENCE | 2021年 / 112卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
OJ14-6-4
引用
收藏
页码：490 / 490
页数：1
相关论文
共 50 条
  • [1] Early administration of amatuximab, a chimeric high-affinity anti-mesothelin monoclonal antibody, suppresses liver metastasis of mesothelin-expressing pancreatic cancer cells and enhances gemcitabine sensitivity in a xenograft mouse model
    Fujii, Yuki
    Kamachi, Hirofumi
    Matsuzawa, Fumihiko
    Mizukami, Tatsuzo
    Kobayashi, Nozomi
    Fukai, Moto
    Taketomi, Akinobu
    [J]. INVESTIGATIONAL NEW DRUGS, 2021, 39 (05) : 1256 - 1266
  • [2] Early administration of amatuximab, a chimeric high-affinity anti-mesothelin monoclonal antibody, suppresses liver metastasis of mesothelin-expressing pancreatic cancer cells and enhances gemcitabine sensitivity in a xenograft mouse model
    Yuki Fujii
    Hirofumi Kamachi
    Fumihiko Matsuzawa
    Tatsuzo Mizukami
    Nozomi Kobayashi
    Moto Fukai
    Akinobu Taketomi
    [J]. Investigational New Drugs, 2021, 39 : 1256 - 1266
  • [3] ImmunoPET with Anti-Mesothelin Antibody in Patients with Pancreatic and Ovarian Cancer before Anti-Mesothelin Antibody-Drug Conjugate Treatment
    Lamberts, Laetitia E.
    van Oordt, Catharina W. Menke-van der Houven
    ter Weele, Eva J.
    Bensch, Frederike
    Smeenk, Michiel M.
    Voortman, Johannes
    Hoekstra, Otto S.
    Williams, Simon P.
    Fine, Bernard M.
    Maslyar, Daniel
    de Jong, Johan R.
    Gietema, Jourik A.
    Schroder, Carolien P.
    Bongaerts, Alphons H. H.
    Lub-de Hooge, Marjolijn N.
    Verheul, Henk M. W.
    Bohorquez, Sandra M. Sanabria
    Glaudemans, Andor W. J. M.
    de Vries, Elisabeth G. E.
    [J]. CLINICAL CANCER RESEARCH, 2016, 22 (07) : 1642 - 1652
  • [4] Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody–drug conjugates from synthetic antibody libraries
    Hung-Ju Hsu
    Chao-Ping Tung
    Chung-Ming Yu
    Chi-Yung Chen
    Hong-Sen Chen
    Yu-Chuan Huang
    Pei-Hsun Tsai
    Su-I Lin
    Hung-Pin Peng
    Yi-Kai Chiu
    Yueh-Liang Tsou
    Wei-Ying Kuo
    Jhih-Wei Jian
    Fei-Hung Hung
    Chiao-Yun Hsieh
    Michael Hsiao
    Simon Shih-Hsien Chuang
    Chia-Ning Shen
    Yong Alison Wang
    An-Suei Yang
    [J]. Scientific Reports, 11
  • [5] Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody-drug conjugates from synthetic antibody libraries
    Hsu, Hung-Ju
    Tung, Chao-Ping
    Yu, Chung-Ming
    Chen, Chi-Yung
    Chen, Hong-Sen
    Huang, Yu-Chuan
    Tsai, Pei-Hsun
    Lin, Su-, I
    Peng, Hung-Pin
    Chiu, Yi-Kai
    Tsou, Yueh-Liang
    Kuo, Wei-Ying
    Jian, Jhih-Wei
    Hung, Fei-Hung
    Hsieh, Chiao-Yun
    Hsiao, Michael
    Chuang, Simon Shih-Hsien
    Shen, Chia-Ning
    Wang, Yong Alison
    Yang, An-Suei
    [J]. SCIENTIFIC REPORTS, 2021, 11 (01)
  • [6] An anti-mesothelin targeting antibody drug conjugate induces pyroptosis and ignites antitumor immunity in mouse models of cancer
    Wittwer, Nicole L.
    Staudacher, Alexander H.
    Liapis, Vasilios
    Cardarelli, Pina
    Warren, Harriet
    Brown, Michael P.
    [J]. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (03)
  • [7] Crizotinib inhibits peritoneal dissemination of pancreatic cancer in a xenograft mouse model
    Takiguchi, Soichi
    Matsusue, Kimihiko
    Teramoto, Norihiro
    Iguchi, Haruo
    [J]. CANCER SCIENCE, 2018, 109 : 1397 - 1397
  • [8] The hen model of human ovarian cancer develops anti-mesothelin autoantibodies in response to mesothelin expressing tumors
    Yu, Yi
    Edassery, Seby L.
    Barua, Animesh
    Abramowicz, Jacques S.
    Bahr, Janice M.
    Hellstrom, Ingegerd
    Luborsky, Judith L.
    [J]. JOURNAL OF OVARIAN RESEARCH, 2011, 4
  • [9] The hen model of human ovarian cancer develops anti-mesothelin autoantibodies in response to mesothelin expressing tumors
    Yi Yu
    Seby L Edassery
    Animesh Barua
    Jacques S Abramowicz
    Janice M Bahr
    Ingegerd Hellstrom
    Judith L Luborsky
    [J]. Journal of Ovarian Research, 4
  • [10] Efficient growth suppression in pancreatic cancer PDX model by fully human anti-mesothelin CAR-T cells
    Hua Jiang
    Bo Song
    Peng Wang
    Bizhi Shi
    Qixiang Li
    Mingliang Fan
    Shengmeng Di
    Jie Yang
    Zonghai Li
    [J]. Protein & Cell., 2017, 8 (12) - 939
12345