A Prospective, Multicenter, Randomized, Trial of Bortezomib/Melphalan/Prednisone (VMP) Versus Bortezomib/Thalidomide/Prednisone (VTP) as Induction Therapy Followed by Maintenance Treatment with Bortezomib/Thalidomide (VT) Versus Bortezomib/Prednisone (VP) in Elderly Untreated Patients with Multiple Myeloma Older Than 65 Years

被引：20

作者：

Mateos, Maria-Victoria

Oriol, Albert ^{[2
]}

Martinez, Joaquin ^{[3
]}

Teresa Cibeira, Ma ^{[4
]}

Gutierrez, Norma C. ^{[1
]}

Jose Terol, Maria ^{[5
]}

de Paz, Raquel ^{[6
]}

Garcia-Larana, Jose ^{[7
]}

Bengoechea, Enrique

Martin Garcia-Sancho, Alejandro ^{[8
]}

Martinez, Rafael ^{[9
]}

Palomera, Luis ^{[10
]}

de Arriba, Felipe ^{[11
]}

Gonzalez, Yolanda ^{[12
]}

Hernandez, Jose ^{[13
]}

Sureda, Anna ^{[14
]}

Bello, Jose-Luis ^{[15
]}

Jose Lahuerta, Juan ^{[16
]}

Blade, Joan ^{[17
]}

San-Miguel, Jesus F. ^{[18
]}

机构：

[1] CSIC, USAL, IBMCC, Hosp Univ Salamanca,CIC, Salamanca, Spain

[2] Hosp Badalona Germans Trias & Pujol, Badalona, Spain

[3] Hosp Doce Octubre, Madrid, Spain

[4] Hosp Clin Barcelona, Barcelona, Spain

[5] Hosp Clin Univ Valencia, Barcelona, Spain

[6] Hosp Univ La Paz, Madrid, Spain

[7] Hosp Ramon & Cajal, E-28034 Madrid, Spain

[8] Hosp Virgen Concha, Zamora, Spain

[9] Hosp Clin San Carlos, Madrid, Spain

[10] Hosp Lozano Blesa, Zaragoza, Spain

[11] Hosp Morales Meseguer, Murcia, Spain

[12] Hosp Josep Trueta, Girona, Spain

[13] Hosp Gen Segovia, Segovia, Spain

[14] Hosp Santa Creu & Sant Pau, Barcelona, Spain

[15] Hosp Clin Univ Santiago Compostela, Santiago De Compostela, Spain

[16] Hosp 12 Octubre, E-28041 Madrid, Spain

[17] IDIBAPS, Hosp Clin, Barcelona, Spain

[18] Hosp Clin Univ Salamanca, Salamanca, Spain

来源：

BLOOD | 2009年 / 114卷 / 22期

关键词：

D O I：

10.1182/blood.V114.22.3.3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：3 / 4

页数：2

共 50 条

[1] Bortezomib, melphalan, and prednisone versus bortezomib, thalidomide, and prednisone as induction therapy followed by maintenance treatment with bortezomib and thalidomide versus bortezomib and prednisone in elderly patients with untreated multiple myeloma: a randomised trial
Mateos, Maria-Victoria
Oriol, Albert
Martinez-Lopez, Joaquin
Gutierrez, Norma
Teruel, Ana-Isabel
de Paz, Raquel
Garcia-Larana, Jose
Bengoechea, Enrique
Martin, Alejandro
Diaz Mediavilla, Joaquin
Palomera, Luis
de Arriba, Felipe
Gonzalez, Yolanda
Hernandez, Jose-Mariano
Sureda, Ana
Bello, Jose-Luis
Bargay, Joan
Penalver, Francisco-Javier
Ribera, Jose-Maria
Martin-Mateos, Maria-Luisa
Garcia-Sanz, Ramon
Cibeira, Maria-Teresa
Martin Ramos, Maria-Luisa
Vidriales, Maria-Belen
Paiva, Bruno
Montalban, Maria-Angeles
Lahuerta, Juan-Jose
Blade, Joan
San Miguel, Jesus-Fernando
[J]. LANCET ONCOLOGY, 2010, 11 (10): : 934 - 941
[2] Bortezomib (Velcade)/Melphalan/Prednisone (VMP) Versus Velcade/Thalidomide/Prednisone (VTP) in Elderly
Mateos, M. V.
Martin, M. L.
Gonzalez, Y.
Lahuerta, J. J.
Blade, J.
Oriol, A.
Martinez, J.
Cibeira, M. T.
de Paz, R.
Terol, M. J.
Garcia, J.
Bengoechea, E.
Martinez, R.
Martin, A.
de Arriba, F.
Palomera, L.
Hernandez, J. M.
Bello, J. L.
San Miguel, J.
[J]. CLINICAL LYMPHOMA & MYELOMA, 2009, 9 : S25 - S25
[3] Safety and efficacy of bortezomib-melphalan-prednisone-thalidomide followed by bortezomib-thalidomide maintenance (VMPT-VT) versus bortezomib-melphalan-prednisone (VMP) in untreated multiple myeloma patients with renal impairment
Morabito, Fortunato
Gentile, Massimo
Mazzone, Carla
Rossi, Davide
Di Raimondo, Francesco
Bringhen, Sara
Ria, Roberto
Offidani, Massimo
Patriarca, Francesca
Nozzoli, Chiara
Petrucci, Maria Teresa
Benevolo, Giulia
Vincelli, Iolanda
Guglielmelli, Tommasina
Grasso, Mariella
Marasca, Roberto
Baldini, Luca
Montefusco, Vittorio
Musto, Pellegrino
Cascavilla, Nicola
Majolino, Ignazio
Musolino, Caterina
Cavo, Michele
Boccadoro, Mario
Palumbo, Antonio
[J]. BLOOD, 2011, 118 (22) : 5759 - 5766
[4] Bortezomib, melphalan, prednisone, and thalidomide (VMPT) followed by maintenance with bortezomib and thalidomide (VT) for initial treatment of elderly multiple myeloma patients
Boccadoro, M.
Bringhen, S.
Gaidano, G.
Ria, R.
Offidani, M.
Patriarca, F.
Nozzoli, C.
Musto, P.
Petrucci, M.
Palumbo, A. P.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15)
[5] Overall Survival Benefit for Bortezomib-Melphalan-Prednisone-Thalidomide Followed by Maintenance with Bortezomib-Thalidomide (VMPT-VT) Versus Bortezomib-Melphalan-Prednisone (VMP) in Newly Diagnosed Multiple Myeloma Patients
Palumbo, Antonio
Bringhen, Sara
Rossi, Dmide
Cavalli, Maide
Ria, Roberto
Gentilini, Silvia
Patriarca, Francesca
Nozzoli, Chiara
Levi, Anna
Guglielmelli, Tommasina
Benevolo, Giulia
Vincelli, Donatella
Baldini, Luca
Morabito, Fortunato
Grasso, Mariella
Marasca, Roberto
Rizzo, Manuela
Pautasso, Chiara
Falcone, Antonietta Pia
Gottardi, Daniela
Montefusco, Vittorio
Musolino, Caterina
Cangialosi, Clotilde
Mansueto, Giovanna
Liberati, Anna Marina
Magarotto, Valeria
Omede, Paola
Musto, Pellegrino
Petrucci, Maria Teresa
Boccadoro, Mario
[J]. BLOOD, 2012, 120 (21)
[6] Bortezomib-Melphalan-Prednisone-Thalidomide Followed by Maintenance With Bortezomib-Thalidomide Compared With Bortezomib-Melphalan-Prednisone for Initial Treatment of Multiple Myeloma: A Randomized Controlled Trial
Palumbo, Antonio
Bringhen, Sara
Rossi, Davide
Cavalli, Maide
Larocca, Alessandra
Ria, Roberto
Offidani, Massimo
Patriarca, Francesca
Nozzoli, Chiara
Guglielmelli, Tommasina
Benevolo, Giulia
Callea, Vincenzo
Baldini, Luca
Morabito, Fortunato
Grasso, Mariella
Leonardi, Giovanna
Rizzo, Manuela
Falcone, Antonietta Pia
Gottardi, Daniela
Montefusco, Vittorio
Musto, Pellegrino
Petrucci, Maria Teresa
Ciccone, Giovannino
Boccadoro, Mario
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (34) : 5101 - 5109
[7] Bortezomib, Melphalan, Prednisone and Thalidomide (VMPT) Followed by Maintenance with Bortezomib and Thalidomide for Initial Treatment of Elderly Multiple Myeloma Patients
Palumbo, Antonio
Bringhen, Sara
Rossi, Davide
Ria, Roberto
Offidani, Massimo
Patriarca, Francesca
Nozzoli, Chiara
Levi, Anna
Guglielmelli, Tommasina
Benevolo, Giulia
Callea, Vincenzo
Olivero, Barbara
Morabito, Fortunato
Grasso, Mariella
Marasca, Roberto
Rizzo, Manuela
Falcone, Antonietta Pia
Gottardi, Daniela
Montefusco, Vittorio
Musolino, Caterina
Zambello, Renato
Cangialosi, Clotilde
Pietrantuono, Giuseppe
Magarotto, Valeria
Petrucci, Maria Teresa
Musto, Pellegrino
Ciccone, Giovannino
Di Raimondo, Francesco
Gaidano, Gianluca
Boccadoro, Mario
[J]. BLOOD, 2009, 114 (22) : 58 - 58
[8] BORTEZOMIB (VELCADE)-MELPHALAN-PREDNISONE (VMP) VERSUS VELCADE-THALIDOMIDE-PREDNISONE (VTP) IN ELDERLY UNTREATED MULTIPLE MYELOMA (MM) PATIENTS
Mateos, M. V.
Oriol, A.
Martinez, J.
Cibeira, M. T.
de Paz, R.
Terol, M. J.
Garcia-Larana, J.
Bengoechea, E.
Martinez, R.
Martin, A.
de Arriba, F.
Palomera, L.
Hernandez, J. M.
Bello, J. L.
Martin, M. L.
Gonzalez, Y.
Lahuerta, J. J.
Blade, J.
San Miguel, J.
[J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 : 190 - 190
[9] BORTEZOMIB-MELPHALAN-PREDNISONE-THALIDOMIDE FOLLOWED BY BORTEZOMIB-THALIDOMIDE MAINTENANCE FOR INITIAL THERAPY OF MULTIPLE MYELOMA: A PROSPECTIVE RANDOMIZED TRIAL
Palumbo, A.
Bringhen, S.
Rossi, D.
Ria, R.
Offidani, M.
Musto, P.
Petrucci, M. T.
Omede, P.
Di Raimondo, F.
Boccadoro, M.
[J]. ANNALS OF ONCOLOGY, 2010, 21 : 350 - 350
[10] BORTEZOMIB, MELPHALAN, PREDNISONE AND THALIDOMIDE (VMPT) VERSUS BORTEZOMIB, MELPHALAN AND PREDNISONE (VMP) IN ELDERLY NEWLY DIAGNOSED MYELOMA PATIENTS: A PROSPECTIVE, RANDOMIZED, PHASE III STUDY
Palumbo, A.
Bringhen, S.
Rossi, D.
Ria, R.
Berretta, S.
Offidani, M.
Patriarca, F.
Nozzoli, C.
Levi, A.
Guglielmelli, T.
Benevolo, G.
Callea, V.
Liberati, A. M.
Crippa, C.
Di Renzo, N.
Catalano, L.
De Sabbata, G.
Rizzi, R.
Feo, C.
Mazza, R.
Farina, G.
Spadano, A.
Pisani, F.
Podda, L.
Aitoro, G.
Magarotto, V.
Astolfi, M.
Di Raimondo, F.
Gaidano, G.
Boccadoro, M.
[J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 : 190 - 191

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