Breaking up is easy to do (if you're a DNA enzyme that cleaves RNA)

被引:19
|
作者
Silverman, SK [1 ]
机构
[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA
来源
CHEMISTRY & BIOLOGY | 2004年 / 11卷 / 01期
关键词
D O I
10.1016/j.chembiol.2004.01.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this issue of Chemistry & Biology, Cruz et al. use in vitro selection to select deoxyribozymes that collectively cleave almost any RNA dinucleotide junction [6]. More remarkable is the finding that the new enzymes are related to the 8-17 deoxyribozyme that cleaves AG dinucleotide junctions.
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页码:7 / 8
页数:2
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