Spectroscopic study of the dispiro-1,2,4,5-tetroxane (cyclohexanone diperoxide)

被引:1
|
作者
Romero, J. M. [1 ]
Jorge, N. L. [1 ]
Gomez-Vara, M. E. [1 ]
Jubert, A. H. [2 ]
Castro, E. A. [3 ]
机构
[1] UNNE, Fac Ciencias Exactas & Nat & Agrimensura, Area Fisicoquim, RA-3400 Corrientes, Argentina
[2] Natl Univ La Plata, Fac Exact Sci, Dept Chem, CEQUINOR, RA-1900 La Plata, Buenos Aires, Argentina
[3] INIFTA, Theoret Chem Div, RA-1900 La Plata, Buenos Aires, Argentina
关键词
dispiro-1,2,4,5-tetroxane; artemisine; antimalarial activity; UV and IR spectra; theoretical study;
D O I
10.1016/j.saa.2007.09.018
中图分类号
O433 [光谱学];
学科分类号
0703 ; 070302 ;
摘要
The aim of this work is to present results derived from experimental IR and UV spectra and theoretical studies of DPCH, in order to get a more deeper insight on the physicochemical properties of this compound to gain a more deep knowledge of its action, helping in the design of new compounds with antimalaric effects. Experimental results are analyzed on the basis of theoretical calculations, which allow to derive suitable interpretations of spectral data. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:775 / 779
页数:5
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