A novel synthesis of 5-functionalized oxazolidin-2-ones from enantiomerically pure 2-substituted N-[(R)-(+)-α-methylbenzyl]aziridines

被引：83

作者：

Sim, TB

Kang, SH

Lee, KS

Lee, WK ^{[1
]}

Yun, H

Dong, YK

Ha, HJ

机构：

[1] Hankuk Univ Foreign Studies, Dept Chem, Yongin 449791, South Korea

[2] Sogang Univ, Dept Chem, Seoul 121742, South Korea

[3] Ajou Univ, Dept Mol Sci & Technol, Suwon 442749, South Korea

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 01期

关键词：

D O I：

10.1021/jo0261911

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

5-Funtionalized enantiomerically pure oxazolidin-2-ones were prepared in one pot from commercially available chiral aziridines bearing an electron-withdrawing group at C-2 with retention of the configuration in high yields by regioselective aziridine ring-opening followed by intramolecular cyclization.

引用

页码：104 / 108

页数：5

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