Nocturnal Pruritus: The Battle for a Peaceful Night's Sleep

被引：82
|
作者：
Lavery, Michael Joseph [1 ]
Stull, Carolyn [1 ]
Kinney, Michael Owen [2 ]
Yosipovitch, Gil [1 ]
机构：
[1] Temple Univ, Lewis Katz Sch Med, Temple Itch Ctr, Dept Dermatol, 3322 North Broad St Suite 212, Philadelphia, PA 19140 USA
[2] Royal Victoria Hosp, Dept Neurosci, 274 Grosvenor Rd, Belfast BT12 6BA, Antrim, North Ireland
来源：
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2016年 / 17卷 / 03期
关键词：
pruritus; sleep; circadian rhythm; atopic dermatitis; sleep cycle; physiology; TRANSEPIDERMAL WATER-LOSS; ATOPIC-DERMATITIS; CLINICAL CHARACTERISTICS; ITCH; DISTURBANCE; MELATONIN; CHILDREN; MIRTAZAPINE; QUALITY; ECZEMA;
D O I：
10.3390/ijms17030425
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Chronic pruritus is a debilitating condition with numerous etiologies. Many patients suffer from nocturnal pruritus, which can decrease quality of life and affect mortality in hemodialysis patients. Nocturnal pruritus may occur in all sleep stages but is most prevalent in stages N1 and N2. Further research is needed to elucidate the pathophysiology of nocturnal itch, which will aid in the development of tailored management strategies.
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页数：12
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