Diagnosis of antiphospholipid syndrome

被引:0
|
作者
Bertolaccini, Maria Laura [1 ,2 ,3 ]
Khamashta, Munther A. [1 ,2 ,3 ]
机构
[1] Guys Hosp, Kings Coll London, Rayne Inst, Lupus Res Unit,Sch Med, London SE1 9RT, England
[2] St Thomas Hosp, London, England
[3] Kings Hosp, Kings Coll London, Rayne Inst, Lupus Res Unit,Sch Med, London, England
关键词
anticardiolipin; antiphospholipid syndrome; heparin; lupus anticoagulant; pregnancy morbidity; thrombosis; warfarin;
D O I
10.1586/17474086.1.2.183
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Antiphospholipid syndrome is a multisystem autoimmune disease, characterized by recurrent vascular thrombosis and/or pregnancy losses in the presence of persistently positive antiphospholipid antibodies. In clinical practice, testing for anticardiolipin antibodies and lupus anticoagulant is mandatory for the laboratory diagnosis of antiphospholipid syndrome. Identification of patients with antiphospholipid syndrome is important, as prophylactic anticoagulant therapy may prevent thrombosis from recurring, and treatment during pregnancy can improve fetal and maternal outcome.
引用
收藏
页码:183 / 188
页数:6
相关论文
共 50 条
  • [1] Diagnosis of antiphospholipid syndrome
    Maria Laura Bertolaccini
    Munther A Khamashta
    Graham RV Hughes
    [J]. Nature Clinical Practice Rheumatology, 2005, 1 : 40 - 46
  • [2] Antiphospholipid syndrome: Diagnosis
    D'Cruz, D. P.
    [J]. REVUE DE MEDECINE INTERNE, 2012, 33 : A5 - A6
  • [3] The diagnosis of the antiphospholipid syndrome
    Pengo, Vittorio
    Ruffatti, Amelia
    Iliceto, Sabino
    [J]. PATHOPHYSIOLOGY OF HAEMOSTASIS AND THROMBOSIS, 2006, 35 (1-2) : 175 - 180
  • [4] Diagnosis of antiphospholipid syndrome
    Bertolaccini, ML
    Khamashta, MA
    Hughes, GRV
    [J]. NATURE CLINICAL PRACTICE RHEUMATOLOGY, 2005, 1 (01): : 40 - 46
  • [5] Role of antiphospholipid antibodies in the diagnosis of antiphospholipid syndrome
    Devreese, Katrien M. J.
    Zuily, Stephane
    Meroni, Pier Luigi
    [J]. JOURNAL OF TRANSLATIONAL AUTOIMMUNITY, 2021, 4
  • [6] ANTIPHOSPHOLIPID ANTIBODIES AND ANTIPHOSPHOLIPID SYNDROME: DIAGNOSIS AND MANAGEMENT
    Garcia-Garcia, C.
    [J]. ACTAS DERMO-SIFILIOGRAFICAS, 2007, 98 (01): : 16 - 23
  • [7] Laboratory diagnosis of the antiphospholipid syndrome
    Wisloff, F
    Jacobsen, EM
    Liestol, S
    [J]. THROMBOSIS RESEARCH, 2002, 108 (5-6) : 263 - 271
  • [8] DIAGNOSIS AND MANAGEMENT OF ANTIPHOSPHOLIPID SYNDROME
    HARRIS, EN
    [J]. HOSPITAL PRACTICE, 1994, 29 (04): : 65 - &
  • [9] Laboratory diagnosis of antiphospholipid syndrome
    Darnige, L.
    [J]. REVUE DE MEDECINE INTERNE, 2006, 27 (04): : 296 - 301
  • [10] Challenges in the Diagnosis of the Antiphospholipid Syndrome
    Devreese, Katrien
    Hoylaerts, Marc F.
    [J]. CLINICAL CHEMISTRY, 2010, 56 (06) : 930 - 940