Guided Bone Regeneration Using Demineralized Dentin Matrix: Long-Term Follow-Up

Purpose: This case report reviews the long-termclinical outcomes of using demineralized dentin matrix (autogenous tooth bone graft material [AutoBT]) in 5 cases that were first reported in 2010. Materials and Methods: Cone-beam computerized tomography was used to measure the height and width of the graft to determine the change in bone area from immediately after surgery to final followup (average, 5 yr 5.8 months). Corticocancellous bone formation and marginal bone resorption also were evaluated histologically 3 to 6 months after grafting, which focused mainly on remodeling capacities. Results: Decreases in buccal height and alveolar ridge width ranged from -0.4 to -3.3 mm and from -0.4 to -4.2 mm, respectively. The change in bone area ranged from -8.1 to -36.2%. Corticocancellous bone had formed and was maintained successfully except for 1 mm of buccal marginal bone resorption in 1 case followed for 6 years 7 months. Conclusion: AutoBT, which was first reported for guided bone regeneration, showed that the corticocancellous bone that had formed had been maintained successfully with an implant after an average follow-up of 5 years. Although the number of samples was small, the results were consistent with those of other short-term follow-up studies on AutoBT. (C) 2016 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 74: 515.e1-515.e9, 2016